BAZ1B Antikörper (Internal Region)

Produktnummer ABIN6260206

Produktdetails anti-BAZ1B Antikörper

Target: BAZ1B (Bromodomain Adjacent To Zinc Finger Domain, 1B (BAZ1B))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAZ1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: BAZ1B Antibody detects endogenous levels of total BAZ1B.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human BAZ1B, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu BAZ1B

Target: BAZ1B (Bromodomain Adjacent To Zinc Finger Domain, 1B (BAZ1B))

Andere Bezeichnung: BAZ1B (BAZ1B Produkte)

Synonyme: BAZ1B antikoerper, wstf antikoerper, wbscr9 antikoerper, wbscr10 antikoerper, LOC100220420 antikoerper, WBSCR10 antikoerper, WBSCR9 antikoerper, WSTF antikoerper, C87820 antikoerper, Wbscr9 antikoerper, fi60d02 antikoerper, im:7137554 antikoerper, wu:fi60d02 antikoerper, bromodomain adjacent to zinc finger domain 1B antikoerper, bromodomain adjacent to zinc finger domain, 1B antikoerper, bromodomain adjacent to zinc finger domain 1B S homeolog antikoerper, BAZ1B antikoerper, baz1b antikoerper, Baz1b antikoerper, baz1b.S antikoerper

Hintergrund:

Description: Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator. Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph). H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. In the complex, it mediates the recruitment of the WICH complex to replication foci during DNA replication.

Gene: BAZ1B

Molekulargewicht: 185 kDa

Gen-ID: 9031

UniProt: Q9UIG0

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding