ATP6V0A2 Antikörper (Internal Region)

Produktnummer ABIN6260132

Produktdetails anti-ATP6V0A2 Antikörper

Target: ATP6V0A2 (ATPase, H+ Transporting, Lysosomal V0 Subunit A2 (ATP6V0A2))

Bindungsspezifität: Internal Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6V0A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: ATP6V0A2 Antibody detects endogenous levels of total ATP6V0A2.

Homologie: Bovine,Horse,Sheep,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ATP6V0A2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ATP6V0A2

Target: ATP6V0A2 (ATPase, H+ Transporting, Lysosomal V0 Subunit A2 (ATP6V0A2))

Andere Bezeichnung: ATP6V0A2 (ATP6V0A2 Produkte)

Synonyme: A2 antikoerper, ARCL antikoerper, ARCL2A antikoerper, ATP6A2 antikoerper, ATP6N1D antikoerper, J6B7 antikoerper, RTF antikoerper, STV1 antikoerper, TJ6 antikoerper, TJ6M antikoerper, TJ6S antikoerper, VPH1 antikoerper, WSS antikoerper, 8430408C20Rik antikoerper, AI385560 antikoerper, ATP6a2 antikoerper, AW489264 antikoerper, Atp6n1d antikoerper, Atp6n2 antikoerper, C76904 antikoerper, ISF antikoerper, SHIF antikoerper, Stv1 antikoerper, TJ6s antikoerper, Tj6 antikoerper, V-ATPase 116 kDa antikoerper, V-ATPase a2 antikoerper, Cc1-3 antikoerper, J6b7 antikoerper, atp6v0a2 antikoerper, si:ch211-199i18.4 antikoerper, si:ch211-106a19.2 antikoerper, ATPase H+ transporting V0 subunit a2 antikoerper, ATPase, H+ transporting, lysosomal V0 subunit A2 antikoerper, ATPase, H+ transporting, lysosomal V0 subunit a2a antikoerper, ATPase, H+ transporting, lysosomal V0 subunit a2b antikoerper, ATP6V0A2 antikoerper, Atp6v0a2 antikoerper, atp6v0a2a antikoerper, atp6v0a2b antikoerper

Hintergrund:

Description: Part of the proton channel of V-ATPases. Essential component of the endosomal  pH -sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi  pH . In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe2+ prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (PubMed:28296633).

Gene: ATP6V0A2

Molekulargewicht: 98 kDa

Gen-ID: 23545

UniProt: Q9Y487

Pathways: Transition Metal Ion Homeostasis, Proton Transport