AKAP10 Antikörper (N-Term)

Produktnummer ABIN6259849

Produktdetails anti-AKAP10 Antikörper

Target: AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKAP10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: AKAP10 Antibody detects endogenous levels of total AKAP10.

Homologie: Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human AKAP10, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu AKAP10

Target: AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))

Andere Bezeichnung: AKAP10 (AKAP10 Produkte)

Synonyme: MGC84612 antikoerper, AKAP10 antikoerper, fc10g11 antikoerper, wu:fc10g11 antikoerper, si:dkey-197m14.4 antikoerper, AKAP-10 antikoerper, D-AKAP-2 antikoerper, D-AKAP2 antikoerper, PRKA10 antikoerper, 1500031L16Rik antikoerper, B130049N18Rik antikoerper, D-akap2 antikoerper, Akap10 antikoerper, A-kinase anchoring protein 10 antikoerper, A-kinase anchoring protein 10 L homeolog antikoerper, A kinase (PRKA) anchor protein 10 antikoerper, AKAP10 antikoerper, akap10.L antikoerper, akap10 antikoerper, Akap10 antikoerper

Hintergrund:

Description: Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity).

Gene: AKAP10

Molekulargewicht: 73kDa

Gen-ID: 11216

UniProt: O43572

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling