AKAP10 Antikörper (Middle Region)

Produktnummer ABIN2775175

Produktdetails anti-AKAP10 Antikörper

Target: AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Kaninchen, Hund, Rind (Kuh), Pferd, Schwein, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKAP10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ESLYQRTYAG KMTFGRVSDL GQFIRESEPE PDVRKSKGSM FSQAMKKWVQ

Homologie: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against AKAP10. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AKAP10

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 662 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AKAP10

Target: AKAP10 (A Kinase (PRKA) Anchor Protein 10 (AKAP10))

Andere Bezeichnung: AKAP10 (AKAP10 Produkte)

Synonyme: MGC84612 antikoerper, AKAP10 antikoerper, fc10g11 antikoerper, wu:fc10g11 antikoerper, si:dkey-197m14.4 antikoerper, AKAP-10 antikoerper, D-AKAP-2 antikoerper, D-AKAP2 antikoerper, PRKA10 antikoerper, 1500031L16Rik antikoerper, B130049N18Rik antikoerper, D-akap2 antikoerper, Akap10 antikoerper, A-kinase anchoring protein 10 antikoerper, A-kinase anchoring protein 10 L homeolog antikoerper, A kinase (PRKA) anchor protein 10 antikoerper, AKAP10 antikoerper, akap10.L antikoerper, akap10 antikoerper, Akap10 antikoerper

Hintergrund: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA, therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction.
Alias Symbols: D-AKAP2, MGC9414, PRKA10
Protein Interaction Partner: COG3, DCTN4, MYH9, PRKAR1A, HAX1, SLC9A3R1, PDZK1, PRKAR2B, PRKAR2A,
Protein Size: 662

Molekulargewicht: 71 kDa

Gen-ID: 11216

NCBI Accession: NM_007202, NP_009133

UniProt: O43572

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling