Prostaglandin D2 Receptor 2 (PTGDR2) (Internal Region) Antikörper
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- Target Alle Prostaglandin D2 Receptor 2 (PTGDR2) Antikörper anzeigen
- Prostaglandin D2 Receptor 2 (PTGDR2)
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- GPR44 Antibody detects endogenous levels of total GPR44.
- Homologie
- Pig,Horse,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human GPR44, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product PTGDR2 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- Prostaglandin D2 Receptor 2 (PTGDR2)
- Andere Bezeichnung
- PTGDR2 (PTGDR2 Produkte)
- Synonyme
- CD294 antikoerper, CRTH2 antikoerper, DL1R antikoerper, DP2 antikoerper, GPR44 antikoerper, Crth2 antikoerper, Grp45 antikoerper, Ptgdr2 antikoerper, Gpr44 antikoerper, prostaglandin D2 receptor 2 antikoerper, PTGDR2 antikoerper, Ptgdr2 antikoerper
- Hintergrund
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Description: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca2+ mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.
Gene: PTGDR2
- Molekulargewicht
- 66 kDa
- Gen-ID
- 11251
- UniProt
- Q9Y5Y4
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
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