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Prostaglandin D2 Receptor 2 (PTGDR2) (Internal Region) Antikörper

PTGDR2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6258740
  • Target Alle Prostaglandin D2 Receptor 2 (PTGDR2) Antikörper anzeigen
    Prostaglandin D2 Receptor 2 (PTGDR2)
    Bindungsspezifität
    • 15
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reaktivität
    • 63
    • 24
    • 13
    • 2
    • 1
    Human
    Wirt
    • 50
    • 13
    • 1
    Kaninchen
    Klonalität
    • 50
    • 14
    Polyklonal
    Konjugat
    • 25
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Unkonjugiert
    Applikation
    • 28
    • 15
    • 14
    • 13
    • 13
    • 12
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Spezifität
    GPR44 Antibody detects endogenous levels of total GPR44.
    Homologie
    Pig,Horse,Dog
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human GPR44, corresponding to a region within the internal amino acids.
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    Prostaglandin D2 Receptor 2 (PTGDR2)
    Andere Bezeichnung
    PTGDR2 (PTGDR2 Produkte)
    Synonyme
    CD294 antikoerper, CRTH2 antikoerper, DL1R antikoerper, DP2 antikoerper, GPR44 antikoerper, Crth2 antikoerper, Grp45 antikoerper, Ptgdr2 antikoerper, Gpr44 antikoerper, prostaglandin D2 receptor 2 antikoerper, PTGDR2 antikoerper, Ptgdr2 antikoerper
    Hintergrund

    Description: Receptor for prostaglandin D2 (PGD2). Coupled to the G(i)-protein. Receptor activation may result in pertussis toxin-sensitive decreases in cAMP levels and Ca2+ mobilization. PI3K signaling is also implicated in mediating PTGDR2 effects. PGD2 induced receptor internalization. CRTH2 internalization can be regulated by diverse kinases such as, PKC, PKA, GRK2, GPRK5/GRK5 and GRK6. Receptor activation is responsible, at least in part, in immune regulation and allergic/inflammation responses.

    Gene: PTGDR2

    Molekulargewicht
    66 kDa
    Gen-ID
    11251
    UniProt
    Q9Y5Y4
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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