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Prostaglandin D2 Receptor 2 (PTGDR2) Antikörper

PTGDR2 Reaktivität: Human FACS Wirt: Ratte Monoclonal BM16 unconjugated
Produktnummer ABIN7505893
  • Target Alle Prostaglandin D2 Receptor 2 (PTGDR2) Antikörper anzeigen
    Prostaglandin D2 Receptor 2 (PTGDR2)
    Reaktivität
    • 65
    • 24
    • 13
    • 4
    • 3
    Human
    Wirt
    • 53
    • 12
    • 1
    Ratte
    Klonalität
    • 53
    • 13
    Monoklonal
    Konjugat
    • 27
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Unkonjugiert
    Applikation
    • 28
    • 18
    • 14
    • 13
    • 13
    • 11
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Verwendungszweck
    Anti-Hu CD294 Purified
    Spezifität
    The rat monoclonal antibody BM16 recognizes an extracellular epitope of CD294 / CRTH2 (prostaglandin D2 receptor 2), a G-protein-coupled seven-transmembrane protein expressed on Th2 cells, peripheral blood basophils and eosinophils.
    Aufreinigung
    Purified by protein-G affinity chromatography.
    Immunogen
    Human CD294 transfected rat cell line TART/B19-12.10
    Klon
    BM16
    Isotyp
    IgG2a
    Top Product
    Discover our top product PTGDR2 Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    Prostaglandin D2 Receptor 2 (PTGDR2)
    Andere Bezeichnung
    CD294 (PTGDR2 Produkte)
    Synonyme
    CD294 antikoerper, CRTH2 antikoerper, DL1R antikoerper, DP2 antikoerper, GPR44 antikoerper, Crth2 antikoerper, Grp45 antikoerper, Ptgdr2 antikoerper, Gpr44 antikoerper, prostaglandin D2 receptor 2 antikoerper, PTGDR2 antikoerper, Ptgdr2 antikoerper
    Hintergrund
    Prostaglandin D2 receptor 2,CD294 (prostaglandin D2 receptor 2) is a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells, but also on eosinophils and basophils. It mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of CD294 gene have been associated with asthma susceptibility. Outside the immune system CD294 is expressed e.g. in gut, heart, and brain. The intracellular C terminal tail contains sites for phosphorylation by protein kinase C.,DP2, PTGDR2, DL1R, CRTH2, GPR44
    Gen-ID
    11251
    UniProt
    Q9Y5Y4
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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