TP53BP2 Antikörper (Internal Region)

Produktnummer ABIN6258732

Produktdetails anti-TP53BP2 Antikörper

Target: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TP53BP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: ASPP2 Antibody detects endogenous levels of total ASPP2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ASPP2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu TP53BP2

Target: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Andere Bezeichnung: TP53BP2 (TP53BP2 Produkte)

Synonyme: 53BP2 antikoerper, ASPP2 antikoerper, BBP antikoerper, P53BP2 antikoerper, PPP1R13A antikoerper, TP53BP2 antikoerper, AI746547 antikoerper, Tp53bp2 antikoerper, X98550 antikoerper, Trp53bp2 antikoerper, wu:fa09h08 antikoerper, wu:fb04e08 antikoerper, zgc:85720 antikoerper, tumor protein p53 binding protein 2 antikoerper, tumor protein p53 binding protein 2 L homeolog antikoerper, tumor protein p53 binding protein, 2b antikoerper, transformation related protein 53 binding protein 2 antikoerper, tumor protein p53 binding protein, 2 antikoerper, tumor protein p53 binding protein, 2a antikoerper, TP53BP2 antikoerper, tp53bp2.L antikoerper, tp53bp2 antikoerper, tp53bp2b antikoerper, Trp53bp2 antikoerper, Tp53bp2 antikoerper, tp53bp2a antikoerper

Hintergrund:

Description: Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Gene: TP53BP2

Molekulargewicht: 170 kDa

Gen-ID: 7159

UniProt: Q13625