CYP1A2 Antikörper (Internal Region)

Produktnummer ABIN6258052

Produktdetails anti-CYP1A2 Antikörper

Target: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP1A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: Cytochrome P450 1A2 Antibody detects endogenous levels of total Cytochrome P450 1A2.

Homologie: Pig,Bovine,Horse,Sheep,Rabbit,Dog

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Cytochrome P450 1A2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu CYP1A2

Target: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Andere Bezeichnung: CYP1A2 (CYP1A2 Produkte)

Synonyme: CP12 antikoerper, P3-450 antikoerper, P450(PA) antikoerper, CYP1A2 antikoerper, CYPIA2 antikoerper, P450-PM4 antikoerper, Cyp1a1 antikoerper, P450-3 antikoerper, CYPD45 antikoerper, P-450d antikoerper, RATCYPD45 antikoerper, CYP1A5 antikoerper, CP450 antikoerper, CYP-IA2 antikoerper, cytochrome P450 family 1 subfamily A member 2 antikoerper, cytochrome P450 1A2 antikoerper, cytochrome P450 LM4 antikoerper, cytochrome P450, family 1, subfamily A, polypeptide 2 antikoerper, cytochrome P450, family 1, subfamily a, polypeptide 2 antikoerper, cytochrome P450 1A2-like antikoerper, CYP1A2 antikoerper, LOC100328937 antikoerper, Cyp1a2 antikoerper, VDBG_06455 antikoerper, LOC101825565 antikoerper, LOC102130662 antikoerper

Hintergrund:

Description: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.

Gene: CYP1A2

Molekulargewicht: 55 kDa

Gen-ID: 1544

UniProt: P05177