CYP1A2 Antikörper (AA 255-282)

Produktnummer ABIN3030672

Produktdetails anti-CYP1A2 Antikörper

Target: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Bindungsspezifität: AA 255-282

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP1A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 255-282 from the human protein was used as the immunogen for this CYP1A2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the CYP1A2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CYP1A2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu CYP1A2

Target: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Andere Bezeichnung: CYP1A2 (CYP1A2 Produkte)

Synonyme: CP12 antikoerper, P3-450 antikoerper, P450(PA) antikoerper, CYP1A2 antikoerper, CYPIA2 antikoerper, P450-PM4 antikoerper, Cyp1a1 antikoerper, P450-3 antikoerper, CYPD45 antikoerper, P-450d antikoerper, RATCYPD45 antikoerper, CYP1A5 antikoerper, CP450 antikoerper, CYP-IA2 antikoerper, cytochrome P450 family 1 subfamily A member 2 antikoerper, cytochrome P450 1A2 antikoerper, cytochrome P450 LM4 antikoerper, cytochrome P450, family 1, subfamily A, polypeptide 2 antikoerper, cytochrome P450, family 1, subfamily a, polypeptide 2 antikoerper, cytochrome P450 1A2-like antikoerper, CYP1A2 antikoerper, LOC100328937 antikoerper, Cyp1a2 antikoerper, VDBG_06455 antikoerper, LOC101825565 antikoerper, LOC102130662 antikoerper

Hintergrund: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, CYP1A2 is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin. [UniProt]

UniProt: P05177