BAG3 Antikörper (Internal Region)
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- Target Alle BAG3 Antikörper anzeigen
- BAG3 (BCL2-Associated Athanogene 3 (BAG3))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BAG3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Spezifität
- BAG3 Antibody detects endogenous levels of total BAG3.
- Homologie
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human BAG3, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product BAG3 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:1000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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- Target
- BAG3 (BCL2-Associated Athanogene 3 (BAG3))
- Andere Bezeichnung
- BAG3 (BAG3 Produkte)
- Synonyme
- bag3-A antikoerper, MGC53113 antikoerper, zgc:100859 antikoerper, BAG3 antikoerper, ATBAG3 antikoerper, BCL-2-associated athanogene 3 antikoerper, T28J14.160 antikoerper, T28J14_160 antikoerper, BAG-3 antikoerper, BIS antikoerper, CAIR-1 antikoerper, MFM6 antikoerper, AA407278 antikoerper, Bis antikoerper, mg638 antikoerper, BCL2 associated athanogene 3 L homeolog antikoerper, BCL2-associated athanogene 3 antikoerper, BCL2 associated athanogene 3 antikoerper, BCL-2-associated athanogene 3 antikoerper, Bcl2-associated athanogene 3 antikoerper, bag3.L antikoerper, bag3 antikoerper, BAG3 antikoerper, Bag3 antikoerper
- Hintergrund
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Description: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70 (PubMed:9873016, PubMed:27474739). Has anti-apoptotic activity (PubMed:10597216). Plays a role in the HSF1 nucleocytoplasmic transport (PubMed:26159920).
Gene: BAG3
- Molekulargewicht
- 62 kDa
- Gen-ID
- 9531
- UniProt
- O95817
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