HINT1 Antikörper (Internal Region)

Produktnummer ABIN6257885

Produktdetails anti-HINT1 Antikörper

Target: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HINT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: HINT1 Antibody detects endogenous levels of total HINT1.

Homologie: Pig,Zebrafish,Bovine,Horse,Rabbit,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HINT1, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu HINT1

Target: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Andere Bezeichnung: HINT1 (HINT1 Produkte)

Synonyme: hint antikoerper, pkci-1 antikoerper, prkcnh1 antikoerper, HINT antikoerper, NMAN antikoerper, PKCI-1 antikoerper, PRKCNH1 antikoerper, AA673479 antikoerper, Hint antikoerper, Ipk1 antikoerper, Pkci antikoerper, Prkci antikoerper, zgc:103764 antikoerper, CHPKCI antikoerper, HINTZ antikoerper, PKCIZ antikoerper, histidine triad nucleotide binding protein 1 antikoerper, histidine triad nucleotide binding protein 1 S homeolog antikoerper, histidine triad nucleotide binding protein 1-Z antikoerper, Histidine triad nucleotide-binding protein 1 antikoerper, HINT1 antikoerper, hint1 antikoerper, Hint1 antikoerper, hint1.S antikoerper, HINT1Z antikoerper, hint-1 antikoerper

Hintergrund:

Description: Hydrolyzes purine nucleotide phosphoramidates with a single phosphate group, including adenosine 5'monophosphoramidate (AMP-NH2), adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, as well as Met-AMP, His-AMP and Asp-AMP, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide. In addition, functions as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex.

Gene: HINT1

Molekulargewicht: 28 kDa

Gen-ID: 3094

UniProt: P49773