HINT1 Antikörper (Middle Region)
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- Target Alle HINT1 Antikörper anzeigen
- HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
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Bindungsspezifität
- AA 59-92, Middle Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HINT1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Histidine triad nucleotide-binding protein 1(HINT1) detection. Tested with WB,IHC-P in Human,Mouse,Rat.
- Sequenz
- HISQISVAED DDESLLGHLM IVGKKCAADL GLNK
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for Histidine triad nucleotide-binding protein 1(HINT1) detection. Tested with WB,IHC-P in Human,Mouse,Rat.
Gene Name: histidine triad nucleotide binding protein 1
Protein Name: Histidine triad nucleotide-binding protein 1 - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence in the middle region of human HINT1 (59-92aa HISQISVAEDDDESLLGHLMIVGKKCAADLGLNK), different from the related mouse and rat sequences by three amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product HINT1 Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))
- Andere Bezeichnung
- HINT1 (HINT1 Produkte)
- Synonyme
- hint antikoerper, pkci-1 antikoerper, prkcnh1 antikoerper, HINT antikoerper, NMAN antikoerper, PKCI-1 antikoerper, PRKCNH1 antikoerper, AA673479 antikoerper, Hint antikoerper, Ipk1 antikoerper, Pkci antikoerper, Prkci antikoerper, zgc:103764 antikoerper, CHPKCI antikoerper, HINTZ antikoerper, PKCIZ antikoerper, histidine triad nucleotide binding protein 1 antikoerper, histidine triad nucleotide binding protein 1 S homeolog antikoerper, histidine triad nucleotide binding protein 1-Z antikoerper, Histidine triad nucleotide-binding protein 1 antikoerper, HINT1 antikoerper, hint1 antikoerper, Hint1 antikoerper, hint1.S antikoerper, HINT1Z antikoerper, hint-1 antikoerper
- Hintergrund
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Histidine triad nucleotide-binding protein 1 is a protein that in humans is encoded by the HINT1 gene. It is a haploinsufficient tumor suppressor gene that inhibits the Wnt/β-catenin pathway in colon cancer cells and Microphthalmia-associated transcription factor (MITF) activity in human mast cells. The protein encoded by this gene can hydrolyze substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. Several transcript variants, but only one of them protein-coding, have been found for this gene.
Synonyms: HINT 1 antibody|HINT1 antibody|HINT1_HUMAN antibody|Histidine triad nucleotide binding protein 1 antibody|Histidine triad nucleotide-binding protein 1 antibody|PKCI 1 antibody|PKCI-1 antibody|PKCI1 antibody|PRKCNH1 antibody|Protein kinase C inhibitor 1 antibody| Protein kinase C interacting protein 1 antibody|Protein kinase C-interacting protein 1 antibody - Gen-ID
- 3094
- UniProt
- P49773
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