XRN1 Antikörper (N-Term)
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- Target Alle XRN1 Antikörper anzeigen
- XRN1 (5'-3' Exoribonuclease 1 (XRN1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser XRN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunocytochemistry (ICC), ELISA, Immunofluorescence (IF)
- Spezifität
- XRN1 Antibody detects endogenous levels of total XRN1.
- Homologie
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human XRN1, corresponding to a region within N-terminal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product XRN1 Primärantikörper
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anti-5'-3' Exoribonuclease 1 (XRN1) (AA 1394-1706) antibody
XRN1 Reaktivität: Human WB, IP, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-5'-3' Exoribonuclease 1 (XRN1) (AA 1567-1723) antibodyXRN1 Reaktivität: Ratte WB, IP, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-5'-3' Exoribonuclease 1 (XRN1) (AA 1389-1423), (C-Term) antibodyXRN1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB49366 unconjugated
anti-5'-3' Exoribonuclease 1 (XRN1) (AA 1455-1706) antibodyXRN1 Reaktivität: Human WB Wirt: Maus Monoclonal 1647CT536-85-48 unconjugated
anti-5'-3' Exoribonuclease 1 (XRN1) (AA 1-459) antibodyXRN1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-5'-3' Exoribonuclease 1 (XRN1) (AA 1260-1309) antibodyXRN1 Reaktivität: Human, Maus, Ratte, Schwein, Kaninchen, Meerschweinchen, Hamster, Affe WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- XRN1 (5'-3' Exoribonuclease 1 (XRN1))
- Andere Bezeichnung
- XRN1 (XRN1 Produkte)
- Synonyme
- wu:fk92c07 antikoerper, zgc:63635 antikoerper, SEP1 antikoerper, Dhm2 antikoerper, exo antikoerper, mXrn1 antikoerper, RGD1309713 antikoerper, 5'-3' exoribonuclease 1 antikoerper, xrn1 antikoerper, XRN1 antikoerper, Tsp_05930 antikoerper, Xrn1 antikoerper
- Hintergrund
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Description: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).
Gene: XRN1
- Molekulargewicht
- 194 kDa
- Gen-ID
- 54464
- UniProt
- Q8IZH2
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