XRN1 Antikörper (AA 1455-1706)

Produktnummer ABIN6242393

Produktdetails anti-XRN1 Antikörper

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Bindungsspezifität: AA 1455-1706

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser XRN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This XRN1 antibody is generated from a mouse immunized with arecombinant protein between1455-1706 amino acids from human XRN1.

Klon: 1647CT536-85-48

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu XRN1

Target: XRN1 (5'-3' Exoribonuclease 1 (XRN1))

Andere Bezeichnung: XRN1 (XRN1 Produkte)

Synonyme: wu:fk92c07 antikoerper, zgc:63635 antikoerper, SEP1 antikoerper, Dhm2 antikoerper, exo antikoerper, mXrn1 antikoerper, RGD1309713 antikoerper, 5'-3' exoribonuclease 1 antikoerper, xrn1 antikoerper, XRN1 antikoerper, Tsp_05930 antikoerper, Xrn1 antikoerper

Hintergrund: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).

Molekulargewicht: 194107

UniProt: Q8IZH2