apg4b antikoerper, APG4B antikoerper, AUTL1 antikoerper, 2510009N07Rik antikoerper, AW048066 antikoerper, Apg4b antikoerper, Atg4bl antikoerper, Autl1 antikoerper, Aut2b2 antikoerper, autophagy related 4B cysteine peptidase antikoerper, autophagy-related 4b antikoerper, Peptidase family C54 protein antikoerper, cysteine protease ATG4B antikoerper, ATG4 autophagy related 4 homolog B (S. cerevisiae) antikoerper, autophagy related 4B, cysteine peptidase antikoerper, autophagy related 4B, cysteine peptidase L homeolog antikoerper, ATG4B antikoerper, Atg4b antikoerper, AT3G59950 antikoerper, Tsp_08582 antikoerper, Tsp_11599 antikoerper, atg4b antikoerper, atg4b.L antikoerper
Hintergrund
Autophagy is the cellular mechanism of degradation and turnover of unnecessary or dysfunctional cellular components. The unneeded components are engulfed in vesicles called autophagosomes, where they are broken down and recycled. The 'autophagy-related gene' ATG4B is a regulator of autophagasome maturation. The microtubule-associated protein LC3-I is lipidated (called LC3-II in its lipidated state) and recruited to the autophagosomal membrane where it is of vital importance in the maturation of autophagosomes. ATG4B regulates LC3-II availability by modulating LC3-I lipidation.