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CD13 Antikörper
ANPEP
Reaktivität: Human
FACS, IF, IHC (fro)
Wirt: Maus
Monoclonal
B-F10
unconjugated
Produktnummer ABIN6252577
Produktdetails anti-CD13 Antikörper
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Target
Alle CD13 (ANPEP) Antikörper anzeigen
CD13 (ANPEP)
(Alanyl (Membrane) Aminopeptidase (ANPEP))
Reaktivität
Alle Reaktivitäten für CD13 Antikörper
Human
Wirt
Alle Wirte für CD13 Antikörper
Maus
Klonalität
Alle Klonalitäten für CD13 Antikörper
Monoklonal
Konjugat
Alle Konjugate für CD13 Antikörper
Dieser CD13 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für CD13 Antikörper
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
Aufreinigung
Protein G affinity chromatography
Immunogen
KG-1 myeloid cells were used as the immunogen for the CD13 antibody.
Klon
B-F10
Isotyp
IgG1 kappa
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Alternativen
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Anwendungsinformationen
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Applikationshinweise
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml Immunofluorescence: 1-2 μg/mL Immunohistochemistry (Frozen): 0.5-1 μg/mL for 30 min at RT Optimal dilution of the CD13 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
0.2 mg/mL
Buffer
PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot and Store at -20C. Avoid freez-thaw cycles.
Details zu CD13
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Target
CD13 (ANPEP)
(Alanyl (Membrane) Aminopeptidase (ANPEP))
Andere Bezeichnung
CD13 (ANPEP Produkte )
Synonyme
APN antikoerper, CD13 antikoerper, GP150 antikoerper, LAP1 antikoerper, P150 antikoerper, PEPN antikoerper, A2AP antikoerper, AAP antikoerper, ALPHA-2-PI antikoerper, API antikoerper, PLI antikoerper, AAT1 antikoerper, ALT1 antikoerper, GPT1 antikoerper, Gpt1 antikoerper, Apn antikoerper, pepN antikoerper, SC8E4A.13 antikoerper, 1300007J06Rik antikoerper, 2310022B03Rik antikoerper, ALT antikoerper, Gpt-1 antikoerper, AP-M antikoerper, AP-N antikoerper, Cd13 antikoerper, Apm antikoerper, KZP antikoerper, Lap1 antikoerper, rAPN antikoerper, APDE antikoerper, p150 antikoerper, anpep antikoerper, fb64c05 antikoerper, wu:fb64c05 antikoerper, zgc:136771 antikoerper, alanyl aminopeptidase, membrane antikoerper, serpin family F member 2 antikoerper, glutamic--pyruvic transaminase antikoerper, aminopeptidase N antikoerper, aminopeptidase antikoerper, aminopeptidase n antikoerper, glutamic pyruvic transaminase, soluble antikoerper, alanyl (membrane) aminopeptidase antikoerper, membrane alanyl aminopeptidase antikoerper, alanyl (membrane) aminopeptidase b antikoerper, alanyl aminopeptidase, membrane L homeolog antikoerper, ANPEP antikoerper, SERPINF2 antikoerper, GPT antikoerper, Gpt antikoerper, Apn2 antikoerper, Apn1 antikoerper, SCO2643 antikoerper, pepN antikoerper, Shewana3_0897 antikoerper, Alvin_1024 antikoerper, Ndas_3413 antikoerper, Saut_1544 antikoerper, Fbal_1877 antikoerper, ML5_3424 antikoerper, Despr_1988 antikoerper, Mesop_5365 antikoerper, Anpep antikoerper, LOC101744250 antikoerper, anpepb antikoerper, anpep.L antikoerper
Hintergrund
Recognizes an integral membrane glycoprotein of 150 kDa, identified as CD13 (also known as aminopeptidase-N). The CD13 antigen is present on most cells of myeloid origin including granulocytes, monocytes, mast cells, and GM-progenitor cells. It is also expressed by the majority of AML, CML in myeloid blast crisis, and in a smaller fraction of lymphoid leukemias. CD13 is absent from normal lymphocytes, platelets and erythrocytes. CD13 is also present on fibroblasts, endothelial cells, epithelial cells from renal proximal tubules and intestinal brush border, bone marrow stromal cells, osteoclasts, and cells lining bile duct canaliculi. CD13 is identical to aminopeptidase N (APN), a prominent membrane-bound metalloprotease present on the surface of intestinal brush border and renal tubules. CD13 plays a role in metabolism of biologically active peptides, in phagocytosis, and in bactericidal/tumoricidal activities. It also serves as a receptor for human coronaviruses (HCV). The lineage-restricted pattern of expression of CD13 within the hemopoietic compartment suggests that it may be important in myeloid cell differentiation.
Gen-ID
290
UniProt
P15144
Pathways
Peptide Hormone Metabolism , Regulation of Systemic Arterial Blood Pressure by Hormones
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