beta-2 Microglobulin Antikörper

Produktnummer ABIN6252361

Produktdetails anti-beta-2 Microglobulin Antikörper

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Reaktivität: Human, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser beta-2 Microglobulin Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Protein G affinity chromatography

Immunogen: Full length recombinant human protein was used as the immunogen for the B2M antibody.

Klon: SPM617

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Immunofluorescence: 0.5-1 μg/mL

Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)

Prediluted format: incubate for 30 min at RT (2)

Optimal dilution of the B2M antibody should be determined by the researcher.

1. Staining of formalin/paraffin tissues requires boiling tissue sections in 10  mM Citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Details zu beta-2 Microglobulin

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Andere Bezeichnung: B2M (B2M Produkte)

Synonyme: Ly-m11 antikoerper, beta2-m antikoerper, beta2m antikoerper, bwm antikoerper, wu:fa94c05 antikoerper, wu:fb10a09 antikoerper, b2m-W01 antikoerper, b2m-W03 antikoerper, b2m-Z01 antikoerper, b2m-Z02 antikoerper, b2m-Z03 antikoerper, B2M antikoerper, b2m antikoerper, B2MG antikoerper, wu:fb66f11 antikoerper, wu:fj01f08 antikoerper, zgc:64161 antikoerper, b-2-m antikoerper, beta-2-microglobulin antikoerper, beta-2 microglobulin antikoerper, beta-2-microglobulin S homeolog antikoerper, beta-2-microglobulin, like antikoerper, B2M antikoerper, B2m antikoerper, b2m antikoerper, b2m.S antikoerper, b2ml antikoerper

Hintergrund: Serum Beta-2 Microglobulin (B2M) levels are a reflection of cell turnover. Levels rise with fever, inflammation, and infection. Increased serum levels are also seen in B-cell malignancies and in renal failure and may indicate a worse prognosis for patients with early-stage Hodgkin's lymphoma.

Gen-ID: 567

UniProt: P61769

Pathways: T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process