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beta-2 Microglobulin Antikörper (AA 21-100)

Name: beta-2 Microglobulin Antikörper (AA 21-100)
Brand: antibodies-online
SKU: ABIN1724930
Price: 614.71 EUR
Availability: InStock

B2M Reaktivität: Human WB, FACS, ELISA, IHC Wirt: Maus Monoclonal 3G5H8 unconjugated

Western blot analysis using B2M mouse mAb against Hela (1), HEK293 (2), HepG2 (3),RAJI (4), A431 (5) and Jurkat (6) cell lysate.

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng),

ELISA

Flow cytometric analysis of A431 cells using B2M mouse mAb (green) and negative control (red).

FACS

Western blot analysis using B2M mAb against human B2M (AA: 21-100) recombinant protein.

Western blot analysis using B2M mAb against HEK293 (1) and B2M (AA: 21-100)-hIgGFc transfected HEK293 (2) cell lysate.

Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using B2M mouse mAb with DAB staining.

IHC

Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using B2M mouse mAb with DAB staining.

IHC

7 Abbildungen

(2 Referenzen)

Produktnummer ABIN1724930

Datenblatt (PDF)

Target Alle beta-2 Microglobulin (B2M) Antikörper anzeigen

beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))
Bindungsspezifität
18

17

15

5

5

5

5

3

2

2

1

1

1

1

1

1
AA 21-100
Reaktivität
207

53

31

27

9

4

4

4

3

2

2

1

1

1

1
Human
Wirt
117

115

11

9

1

1
Maus
Passende Sekundärantikörper
Klonalität
137

116

1
Monoklonal
Konjugat
112

33

26

16

13

9

3

3

3

3

3

3

3

3

3

3

3

3

3

1

1

1

1

1

1
Dieser beta-2 Microglobulin Antikörper ist unkonjugiert
Applikation
129

115

73

64

62

43

41

32

27

18

17

15

13

12

6

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)

Aufreinigung

purified

Immunogen

Purified recombinant fragment of human B2M (AA: 21-100) expressed in E. coli.

Klon

3G5H8

Isotyp

IgG2a
anti-beta-2-Microglobulin (B2M) (AA 21-100) antibody
B2M Reaktivität: Human WB, FACS, ELISA, IHC, ICC Wirt: Maus Monoclonal 4G5A1 unconjugated

anti-beta-2-Microglobulin (B2M) (AA 1-119) antibody
B2M Reaktivität: Human WB, ELISA, IF, IHC (p), RNAi, PLA Wirt: Maus Monoclonal 3F9-2C2 unconjugated

anti-beta-2-Microglobulin (B2M) antibody
B2M Reaktivität: Human WB, FACS, ELISA, IP, IHC (p), ICC, RIA Wirt: Maus Monoclonal B2M-01 unconjugated

anti-beta-2-Microglobulin (B2M) (AA 22-119) antibody
B2M Reaktivität: Maus WB, IHC, IP, ICC Wirt: Maus Monoclonal A2 unconjugated

anti-beta-2-Microglobulin (B2M) (AA 22-119) antibody
B2M Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-beta-2-Microglobulin (B2M) antibody
B2M Reaktivität: Human, Non-Human Primate FACS, IHC, IF, StM Wirt: Maus Monoclonal rB2M-961 unconjugated Recombinant Antibody

anti-beta-2-Microglobulin (B2M) antibody
B2M Reaktivität: Human, Non-Human Primate IHC, StM Wirt: Maus Monoclonal B2M-1118 unconjugated

anti-beta-2-Microglobulin (B2M) antibody
B2M Reaktivität: Human, Non-Human Primate WB, FACS, IHC, IF, StM Wirt: Maus Monoclonal B2M-961 unconjugated

anti-beta-2-Microglobulin (B2M) antibody (Biotin)
B2M Reaktivität: Human WB, FACS, ELISA, IP, IHC (p), ICC Wirt: Maus Monoclonal B2M-01 Biotin

anti-beta-2-Microglobulin (B2M) antibody
B2M Reaktivität: Human, Non-Human Primate FACS, IF, IHC (p) Wirt: Maus Monoclonal B2M-961 unconjugated

Applikationshinweise

ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

4°C, -20°C for long term storage
Bernal, Ruiz-Cabello, Concha, Paschen, Garrido: "Implication of the ?2-microglobulin gene in the generation of tumor escape phenotypes." in: Cancer immunology, immunotherapy : CII, Vol. 61, Issue 9, pp. 1359-71, (2012) (PubMed).

Hermansen, Hummelshøj, Lundsgaard, Hornum, Keller, Fleckner, Fox, Poulsen, Jacobsen: "Increased serum ?2-microglobulin is associated with clinical and immunological markers of disease activity in systemic lupus erythematosus patients." in: Lupus, Vol. 21, Issue 10, pp. 1098-104, (2012) (PubMed).
Target

beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Andere Bezeichnung

B2M (B2M Produkte)

Synonyme

Ly-m11 antikoerper, beta2-m antikoerper, beta2m antikoerper, bwm antikoerper, wu:fa94c05 antikoerper, wu:fb10a09 antikoerper, b2m-W01 antikoerper, b2m-W03 antikoerper, b2m-Z01 antikoerper, b2m-Z02 antikoerper, b2m-Z03 antikoerper, B2M antikoerper, b2m antikoerper, B2MG antikoerper, wu:fb66f11 antikoerper, wu:fj01f08 antikoerper, zgc:64161 antikoerper, b-2-m antikoerper, beta-2-microglobulin antikoerper, beta-2 microglobulin antikoerper, beta-2-microglobulin S homeolog antikoerper, beta-2-microglobulin, like antikoerper, B2M antikoerper, B2m antikoerper, b2m antikoerper, b2m.S antikoerper, b2ml antikoerper

Hintergrund

This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia. ,

Molekulargewicht

13.7 kDa

Gen-ID

567

HGNC

567

Pathways

T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process