Transferrin Receptor Antikörper (Extracellular Domain)

Produktnummer ABIN6252237

Produktdetails anti-Transferrin Receptor Antikörper

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Bindungsspezifität: AA 94-212, Extracellular Domain

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Transferrin Receptor Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Protein G affinity chromatography

Immunogen: Amino acids 94-212 (extracellular domain) of the human protein were used as the immunogen for the Transferrin Receptor antibody.

Klon: TFRC-1818

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: WB: 0.5-1 μg/mL

ELISA: 2-4 μg/mL, order the BSA free formulation for coating

Flow Cytometry: 0.5-1 μg/million cells in 0.1ml

Immunofluorescence: 1-2 μg/mL

IHC (FFPE): 1-2 μg/mL for 30 min at RT

Optimal dilution of the Transferrin Receptor antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: PBS with 0.1 mg/mL BSA and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and Store at -20C. Avoid freez-thaw cycles.

Details zu Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung: Transferrin Receptor (TFRC Produkte)

Synonyme: Trfr antikoerper, LOC100219280 antikoerper, tfr antikoerper, cd71 antikoerper, tfr1 antikoerper, trfr antikoerper, CD71 antikoerper, T9 antikoerper, TFR antikoerper, TFR1 antikoerper, TR antikoerper, TRFR antikoerper, p90 antikoerper, 2610028K12Rik antikoerper, AI195355 antikoerper, AI426448 antikoerper, AU015758 antikoerper, E430033M20Rik antikoerper, Mtvr-1 antikoerper, Mtvr1 antikoerper, transferrin receptor antikoerper, TFRC antikoerper, Tfrc antikoerper, tfrc antikoerper

Hintergrund: It recognizes a ~85-95  kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190  kDa. This mAb is highly specific to Transferrin Receptor / CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin Receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Gen-ID: 7037

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis