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Transferrin Receptor Antikörper

Name: Transferrin Receptor Antikörper
Brand: antibodies-online
SKU: ABIN94221
Price: 300.56 EUR
Availability: InStock

TFRC Reaktivität: Human FACS, IP, ICC Wirt: Maus Monoclonal MEM-75 unconjugated

Flow cytometry surface staining pattern of human PHA stimulated peripheral blood mononuclear cells stained using anti-human CD71 (MEM-75) purified antibody (concentration in sample 0.

FACS

Surface staining of NALM-6 human peripheral blood pre-B cell leukemia cell line with anti-CD71 (MEM-75) biotin; detection by Streptavidin-PE .

FACS

Immunofluorescence staining of CD71 in human HeLa cell line using anti-CD71 (; green).

Immunocytochemistry staining of CD71 in human HeLa cell line using anti-CD71 (MEM-75, green).

ICC

Flow cytometry multicolor surface staining pattern of human PHA stimulated lymphocytes using anti-human CD3 (UCHT1) PE antibody (20 μL reagent / 100 μL of peripheral whole blood) and anti-human CD71 (MEM-75) purified antibody (concentration in sample 0.

FACS

Separation of human CD3 positive CD71 positive lymphocytes (red-filled) from CD3 negative CD71 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human PHA stimulated peripheral blood mononuclear cells stained using anti-human CD71 (MEM-75) purified antibody (concentration in sample 0.

FACS

6 Abbildungen

(1 reference)

Produktnummer ABIN94221

Datenblatt (PDF)

Target Alle Transferrin Receptor (TFRC) Antikörper anzeigen

Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
Reaktivität
195

81

28

7

6

4

2

2

2

1

1

1

1
Human
Wirt
110

108

31

1

1
Maus
Passende Sekundärantikörper
Klonalität
155

94

1
Monoklonal
Konjugat
110

27

20

15

10

5

5

4

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Dieser Transferrin Receptor Antikörper ist unkonjugiert
Applikation
153

139

72

68

54

40

23

21

19

12

7

6

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Spezifität

The antibody MEM-75 reacts with an extracellular epitope of CD71 antigen (transferrin receptor), a 95 kDa type II homodimeric transmembrane glycoprotein expressed on activated B and T lymphocytes, macrophages and erythroid precursors, it is lost on resting blood leukocytes. The antibody MEM-75 does not block binding of transferrin to the receptor.

Kreuzreaktivität (Details)

Human

Aufreinigung

Purified by protein-A affinity chromatography.

Reinheit

> 98 % (by SDS-PAGE)

Immunogen

NALM-6 human pre-B cell line

Klon

MEM-75

Isotyp

IgG1
anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 578-765) antibody
TFRC Reaktivität: Schwein WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) antibody
TFRC Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 1-140) antibody
TFRC Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) antibody (Biotin)
TFRC Reaktivität: Human FACS, IP, ICC Wirt: Maus Monoclonal MEM-75 Biotin

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 649-677), (C-Term) antibody
TFRC Reaktivität: Human FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal RB20736 unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 608-727) antibody
TFRC Reaktivität: Human, Maus, Ratte, Affe WB, ELISA Wirt: Maus Monoclonal 1A1B2 unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 68-168) antibody
TFRC Reaktivität: Human WB, ELISA, IHC (p) Wirt: Maus Monoclonal 1E6 unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 567-744) antibody
TFRC Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 572-757) antibody
TFRC Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Transferrin Receptor (p90, CD71) (TFRC) (AA 567-744) antibody
TFRC Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal unconjugated

Applikationshinweise

Flow cytometry: Recommended dilution: 0.5-4 μg/mL.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1 mg/mL

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Do not freeze.

Lagerung

4 °C

Informationen zur Lagerung

Store at 2-8°C. Do not freeze.
Beck, Balogh, Kis, Izsépi, Cervenak, László, Bíró, Liliom, Mocsár, Vámosi, Füst, Matko: "New cholesterol-specific antibodies remodel HIV-1 target cells' surface and inhibit their in vitro virus production." in: Journal of lipid research, Vol. 51, Issue 2, pp. 286-96, (2010) (PubMed).
Target

Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Andere Bezeichnung

CD71 (TFRC Produkte)

Synonyme

Trfr antikoerper, LOC100219280 antikoerper, tfr antikoerper, cd71 antikoerper, tfr1 antikoerper, trfr antikoerper, CD71 antikoerper, T9 antikoerper, TFR antikoerper, TFR1 antikoerper, TR antikoerper, TRFR antikoerper, p90 antikoerper, 2610028K12Rik antikoerper, AI195355 antikoerper, AI426448 antikoerper, AU015758 antikoerper, E430033M20Rik antikoerper, Mtvr-1 antikoerper, Mtvr1 antikoerper, transferrin receptor antikoerper, TFRC antikoerper, Tfrc antikoerper, tfrc antikoerper

Hintergrund

Transferrin receptor,CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions), CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH . CD71 is also involved in uptake of non-transferrin bound iron.,TfR1, TfR, TR, Trfr, T9, p90, TFRC

Gen-ID

7037

UniProt

P02786

Pathways

Transition Metal Ion Homeostasis