This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This PPP1R13L antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 455-485 amino acids from the Central region of human PPP1R13L.
AV260376 antikoerper, IASPP antikoerper, Nkip1 antikoerper, wa3 antikoerper, zgc:113058 antikoerper, NKIP1 antikoerper, RAI antikoerper, RAI4 antikoerper, protein phosphatase 1, regulatory (inhibitor) subunit 13 like antikoerper, protein phosphatase 1, regulatory subunit 13 like antikoerper, protein phosphatase 1 regulatory subunit 13 like antikoerper, protein phosphatase 1 regulatory subunit 13 like L homeolog antikoerper, Ppp1r13l antikoerper, ppp1r13l antikoerper, PPP1R13L antikoerper, ppp1r13l.L antikoerper
Hintergrund
Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.