This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CTDSP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 16-50 amino acids from the N-terminal region of human CTDSP1.
CTDSP1 antikoerper, NIF3 antikoerper, NLI-IF antikoerper, NLIIF antikoerper, SCP1 antikoerper, fj83f12 antikoerper, im:7141428 antikoerper, wu:fj83f12 antikoerper, zgc:113169 antikoerper, GIP antikoerper, Nif3 antikoerper, CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 antikoerper, CTD small phosphatase 1 antikoerper, carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 antikoerper, CTDSP1 antikoerper, Ctdsp1 antikoerper, ctdsp1 antikoerper, HCAG_04820 antikoerper, CTRG_06220 antikoerper
Hintergrund
Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.