PAX7 Antikörper (AA 300-600) (CF®647)
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- Target Alle PAX7 Antikörper anzeigen
- PAX7 (Paired Box 7 (PAX7))
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Bindungsspezifität
- AA 300-600
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PAX7 Antikörper ist konjugiert mit CF®647
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Applikation
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Verwendungszweck
- Mouse Monoclonal anti-PAX7 (PAX7/1187), CF647 Conjugate
- Produktmerkmale
- The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Recombinant fragment (aa300-600) of human PAX7 protein
- Klon
- PAX7-1187
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product PAX7 Primärantikörper
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- Applikationshinweise
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Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
- Optimal dilution for a specific application should be determined by user
- Kommentare
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Rhabdomyosarcoma (RMS) or Testicular Carcinoma
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
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- Target
- PAX7 (Paired Box 7 (PAX7))
- Andere Bezeichnung
- PAX7 (PAX7 Produkte)
- Synonyme
- PAX7 antikoerper, HUP1 antikoerper, PAX7B antikoerper, RMS2 antikoerper, pax-7 antikoerper, PAX-7 antikoerper, RGD1564360 antikoerper, Pax-7 antikoerper, pax7 antikoerper, pax7c antikoerper, pax7d antikoerper, pax7e antikoerper, paired box 7 antikoerper, paired box protein Pax-7 antikoerper, paired box 7 L homeolog antikoerper, paired box 7a antikoerper, PAX7 antikoerper, pax7.L antikoerper, LOC536229 antikoerper, Pax7 antikoerper, pax7a antikoerper
- Hintergrund
- HUP1, Paired box gene 7, Paired box homeotic gene 7, Paired domain gene HuP1, PAX7 transcriptional factor, PAX7/FKHR fusion gene, PAX7B, RMS2
- Molekulargewicht
- 57 kDa
- Gen-ID
- 5081, 113253
- UniProt
- P23759
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