PAX7 Antikörper (N-Term)

Produktnummer ABIN2779615

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-PAX7 Antikörper wird verwendet zum Nachweis von PAX7 in Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Rind (Kuh) und Kaninchen. Er wurde validiert für WB und IHC.

Kurzübersicht für PAX7 Antikörper (N-Term) (ABIN2779615)

Target: PAX7 (Paired Box 7 (PAX7))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Meerschweinchen, Rind (Kuh), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAX7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PAX7 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PAX7 Antibody - N-terminal region

Sequenz: KEEEDEADKK EDDGEKKAKH SIDGILGDKG NRLDEGSDVE SEPDLPLKRK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PAX7. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PAX7

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32393-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PAX7 Antikörper (ABIN2779615)

McDonald, Kunz, McLoon: "Dystrophic changes in extraocular muscles after gamma irradiation in mdx:utrophin(+/-) mice." in: PLoS ONE, Vol. 9, Issue 1, pp. e86424, (2014) (PubMed).

Details zu PAX7

Target: PAX7 (Paired Box 7 (PAX7))

Andere Bezeichnung: PAX7

Hintergrund:

Background Information: PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box gene 7 is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.

Gene Name: Paired box 7

Alternative Symbols: HUP1, RMS2, PAX7B, MYOSCO

Protein Name: Paired box protein Pax-7

Molekulargewicht: 55 kDa

Gen-ID: 5081

NCBI Accession: NP_002575

UniProt: P23759