MYB Antikörper (AA 119-135) (CF®488A)
-
- Target Alle MYB Antikörper anzeigen
- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
-
Bindungsspezifität
- AA 119-135
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser MYB Antikörper ist konjugiert mit CF®488A
-
Applikation
- Immunofluorescence (IF), Flow Cytometry (FACS)
- Verwendungszweck
- Mouse Monoclonal anti-c-Myb (MYB286), CF488A Conjugate
- Produktmerkmale
- The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- A synthetic peptide, corresponding to aa 119-135 (RRKVEQEGYPQESSKAG) of c-myb oncoprotein, coupled to KLH
- Klon
- MYB286
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product MYB Primärantikörper
-
-
- Applikationshinweise
-
Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
-
Jurkat, MOLT-4, COLO or BT-20 cells. Colon or breast carcinomas.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
-
- Target
- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
- Andere Bezeichnung
- c-Myb (MYB Produkte)
- Synonyme
- Cmyb antikoerper, c-myb antikoerper, c-myb_CDS antikoerper, efg antikoerper, AI550390 antikoerper, M16449 antikoerper, cmyb antikoerper, xmyb antikoerper, MYB proto-oncogene, transcription factor antikoerper, myeloblastosis oncogene antikoerper, MYB proto-oncogene, transcription factor S homeolog antikoerper, v-myb avian myeloblastosis viral oncogene homolog antikoerper, MYB antikoerper, Myb antikoerper, myb.S antikoerper, myb antikoerper
- Hintergrund
- C-myb_CDS, efg, ONCOGENE AMV, Oncogene MYB, Proto-oncogene c-Myb, Transcriptional activator Myb, v-myb avian myeloblastosis viral oncogene homolog
- Molekulargewicht
- 75 kDa
- Gen-ID
- 4602, 606320
- UniProt
- P01104
- Pathways
- Chromatin Binding, Positive Regulation of Immune Effector Process
-