MUC6 Antikörper

Produktnummer ABIN6186835

Produktdetails anti-MUC6 Antikörper

Target: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MUC6 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Verwendungszweck: Mouse Monoclonal anti-Mucin 6 (MUC6) (MUC6/916), Purified, with BSA

Produktmerkmale: The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2, Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Aufreinigung: Purified

Immunogen: Recombinant human MUC6 protein

Klon: MUC6-916

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Does not react with rat, others not known

• Immunohistology formalin-fixed 2-4 μg/mL
• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Immunofluorescence 1-2 μg/mL
• Western blotting 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

Stomach

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 200 μg/mL

Buffer: PBS/0.05 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu MUC6

Target: MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))

Andere Bezeichnung: Mucin 6 (MUC6 Produkte)

Synonyme: gastric antikoerper, MUC-6 antikoerper, mucin-6-like antikoerper, mucin 6, oligomeric mucus/gel-forming antikoerper, mucin 6, gastric antikoerper, LOC100850574 antikoerper, MUC6 antikoerper, Muc6 antikoerper

Hintergrund: Gastric mucin 6, MUC6, MUC6 mucin, Mucin 6 oligomeric mucus/gel forming, Mucin glycoprotein Fragment, Mucin-6, Secretory mucin MUC6

Molekulargewicht: 252 kDa

Gen-ID: 4588, 528432

UniProt: Q6W4X9