CDX2 Antikörper (AA 150-249) (CF®488A)
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- Target Alle CDX2 Antikörper anzeigen
- CDX2 (Caudal Type Homeobox 2 (CDX2))
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Bindungsspezifität
- AA 150-249
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CDX2 Antikörper ist konjugiert mit CF®488A
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Applikation
- ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)
- Verwendungszweck
- Mouse Monoclonal anti-CDX2 (CDX2/1690), CF488A Conjugate
- Produktmerkmale
- The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Recombinant human CDX2 protein fragment (aa150-249) (exact sequence is proprietary)
- Klon
- CDX2-1690
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product CDX2 Primärantikörper
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- Applikationshinweise
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ELISA 2-4 μg/mL for coating (order Ab without BSA)
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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HT29 cells or Colon Carcinoma
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
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- Target
- CDX2 (Caudal Type Homeobox 2 (CDX2))
- Andere Bezeichnung
- CDX2 (CDX2 Produkte)
- Synonyme
- CDX2 antikoerper, MGC130987 antikoerper, cdx3-like antikoerper, CDX-3 antikoerper, CDX3 antikoerper, CDX-2 antikoerper, Cdx-2 antikoerper, caudal type homeobox 2 antikoerper, caudal type homeobox 2 L homeolog antikoerper, caudal type homeo box 2 antikoerper, CDX2 antikoerper, cdx2.L antikoerper, Cdx2 antikoerper
- Hintergrund
- Caudal type homeobox 2, Caudal type homeobox transcription factor 2, Caudal-type homeobox protein 2, CDX2
- Molekulargewicht
- 40 kDa
- Gen-ID
- 1045, 174249
- UniProt
- Q99626
- Pathways
- Peptide Hormone Metabolism, Stem Cell Maintenance
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