CDX2 Antikörper (AA 150-249) (CF®640R)

Produktnummer ABIN6182852

Produktdetails anti-CDX2 Antikörper (CF®640R)

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Bindungsspezifität: AA 150-249

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CDX2 Antikörper ist konjugiert mit CF®640R

Applikation: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)

Verwendungszweck: Mouse Monoclonal anti-CDX2 (CDX2/1690), CF640R Conjugate

Produktmerkmale: The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant human CDX2 protein fragment (aa150-249) (exact sequence is proprietary)

Klon: CDX2-1690

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: ELISA 2-4 μg/mL for coating (order Ab without BSA)

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Immunofluorescence 1-2 μg/mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

HT29 cells or Colon Carcinoma

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu CDX2

Target: CDX2 (Caudal Type Homeobox 2 (CDX2))

Andere Bezeichnung: CDX2 (CDX2 Produkte)

Synonyme: CDX2 antikoerper, MGC130987 antikoerper, cdx3-like antikoerper, CDX-3 antikoerper, CDX3 antikoerper, CDX-2 antikoerper, Cdx-2 antikoerper, caudal type homeobox 2 antikoerper, caudal type homeobox 2 L homeolog antikoerper, caudal type homeo box 2 antikoerper, CDX2 antikoerper, cdx2.L antikoerper, Cdx2 antikoerper

Hintergrund: Caudal type homeobox 2, Caudal type homeobox transcription factor 2, Caudal-type homeobox protein 2, CDX2

Molekulargewicht: 40 kDa

Gen-ID: 1045, 174249

UniProt: Q99626

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance