Fibronectin Antikörper (CF®640R)

Produktnummer ABIN6168754

Produktdetails anti-Fibronectin Antikörper (CF®640R)

Target: Fibronectin

Reaktivität: Human, Maus, Ratte, Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Fibronectin Antikörper ist konjugiert mit CF®640R

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Verwendungszweck: Mouse Monoclonal anti-Fibronectin (TV-1), CF640R Conjugate

Produktmerkmale: Fibronectin is a soluble dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating MAb indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: T-cell lymphoma biopsy

Klon: TV-1

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Immunohistology formalin-fixed 0.5-1 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA,  pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
• Immunofluorescence 0.5-1 μg/mL
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

SW156 cells or Kidney

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from light

Details zu Fibronectin

Target: Fibronectin

Abstract: Fibronectin Produkte

Synonyme: FN antikoerper, cig antikoerper, fibronectin antikoerper, finc antikoerper, lets antikoerper, msf antikoerper, CIG antikoerper, ED-B antikoerper, FINC antikoerper, FNZ antikoerper, GFND antikoerper, GFND2 antikoerper, LETS antikoerper, MSF antikoerper, E330027I09 antikoerper, Fn antikoerper, Fn-1 antikoerper, FIBNEC antikoerper, fn-1 antikoerper, fibronectin 1 antikoerper, FN1 antikoerper, fn1 antikoerper, Fn1 antikoerper

Hintergrund: Cold insoluble globulin (CIG), FINC, FN1, FNZ, GFND, GFND2, LETS, Migration stimulating factor (MSF), Ugl-Y3

Molekulargewicht: 220 kDa (monomer), 440 kDa (dimer)

Gen-ID: 2335, 203717

UniProt: P02751