NADPH Oxidase 4 Antikörper (CF®405S)
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- Target Alle NADPH Oxidase 4 (NOX4) Antikörper anzeigen
- NADPH Oxidase 4 (NOX4)
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser NADPH Oxidase 4 Antikörper ist konjugiert mit CF®405S
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Coating (Coat)
- Verwendungszweck
- Mouse Monoclonal anti-NOX4 / NADPH-Oxidase-4 (NOX4/1245), CF405S Conjugate
- Produktmerkmale
- The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Recombinant human NOX4 protein
- Klon
- NOX4-1245
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product NOX4 Primärantikörper
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- Applikationshinweise
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Western blotting 0.5-1 μg/mL
- ELISA For coating, order Ab without BSA
- Optimal dilution for a specific application should be determined by user
- Kommentare
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PC-12, JAR cells. Kidney
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
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- Target
- NADPH Oxidase 4 (NOX4)
- Andere Bezeichnung
- NOX4 / NADPH-Oxidase-4 (NOX4 Produkte)
- Synonyme
- KOX antikoerper, KOX-1 antikoerper, RENOX antikoerper, AI648021 antikoerper, nox4 antikoerper, NOX4 antikoerper, NADPH oxidase 4 antikoerper, NOX4 antikoerper, Nox4 antikoerper, nox4 antikoerper, PTRG_09562 antikoerper
- Hintergrund
- Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, KOX-1, NADPH oxidase 4, Nox4, Renal NAD(P)H-oxidase, RENOX
- Molekulargewicht
- 70 kDa
- Gen-ID
- 50507, 371036
- UniProt
- Q9NPH5
- Pathways
- Carbohydrate Homeostasis, Smooth Muscle Cell Migration
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