NADPH Oxidase 4 Antikörper (AA 81-180)

Produktnummer ABIN737526

Zitiert in 3+ Publikationen. Der Kaninchen Polyklonal anti-NADPH Oxidase 4 Antikörper (ABIN737526) detektiert spezifisch NADPH Oxidase 4 in WB, FACS, IP, IHC (p), IF (p), IF (cc) und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für NADPH Oxidase 4 Antikörper (AA 81-180) (ABIN737526)

Target: NADPH Oxidase 4 (NOX4)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NADPH Oxidase 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-NADPH Oxidase 4 Antikörper

Bindungsspezifität: AA 81-180

Verwendungszweck: NADPH oxidase 4 Polyclonal Antibody

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Nox-4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000),

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-NADPH Oxidase 4 Antikörper (ABIN737526)

Ulmasov, Bruno, Oshima, Cheng, Holly, Parise, Egan, Edwards: "CLIC1 null mice demonstrate a role for CLIC1 in macrophage superoxide production and tissue injury." in: Physiological reports, Vol. 5, Issue 5, (2017) (PubMed).

Khan, Byer, Khan: "Exposure of Madin-Darby canine kidney (MDCK) cells to oxalate and calcium oxalate crystals activates nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase." in: Urology, Vol. 83, Issue 2, pp. 510.e1-7, (2014) (PubMed).

Details zu NADPH Oxidase 4

Target: NADPH Oxidase 4 (NOX4)

Andere Bezeichnung: NADPH oxidase 4

Hintergrund:

Synonyms: AI64821, NADPH oxidase 4, Kidney oxidase-1, KOX-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase, Superoxide-generating NADPH oxidase 4, Nox4, Renox

Background: Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.

Gen-ID: 50490

UniProt: Q9JHI8

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration