NADPH Oxidase 4 Antikörper

Produktnummer ABIN6940247

Der Maus Monoklonal anti-NADPH Oxidase 4 Antikörper wird verwendet zum Nachweis von NADPH Oxidase 4 in Proben von Human. Er wurde validiert für WB und ELISA.

Kurzübersicht für NADPH Oxidase 4 Antikörper (ABIN6940247)

Target: NADPH Oxidase 4 (NOX4)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NADPH Oxidase 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: NOX4-1245

Produktdetails anti-NADPH Oxidase 4 Antikörper

Verwendungszweck: NOX4 / NADPH Oxidase 4 Antibody

Spezifität: The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human NOX4 protein

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: PC-12, JAR cells. Kidney.

Known Application: ELISA (For coating, order Ab without BSA)Western Blot (0.5-1 μg/mL)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu NADPH Oxidase 4

Target: NADPH Oxidase 4 (NOX4)

Andere Bezeichnung: NOX4

Hintergrund:

Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, KOX-1, NADPH oxidase 4, Nox4, Renal NAD(P)H-oxidase, RENOX

JAR cells. Kidney., PC-12

Molekulargewicht: 70kDa

Gen-ID: 50507, 371036

UniProt: Q9NPH5

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration