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NADPH Oxidase 4 Antikörper

NOX4 Reaktivität: Human WB, ELISA, Coat Wirt: Maus Monoclonal NOX4-1245 unconjugated
Produktnummer ABIN6940247
  • Target Alle NADPH Oxidase 4 (NOX4) Antikörper anzeigen
    NADPH Oxidase 4 (NOX4)
    Reaktivität
    • 93
    • 40
    • 36
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 83
    • 15
    Maus
    Klonalität
    • 74
    • 25
    Monoklonal
    Konjugat
    • 35
    • 10
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NADPH Oxidase 4 Antikörper ist unkonjugiert
    Applikation
    • 82
    • 42
    • 41
    • 25
    • 18
    • 14
    • 13
    • 13
    • 9
    • 8
    • 7
    • 3
    • 3
    Western Blotting (WB), ELISA, Coating (Coat)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant human NOX4 protein
    Klon
    NOX4-1245
    Isotyp
    IgG2b kappa
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    Discover our top product NOX4 Primärantikörper
  • Applikationshinweise

    Positive Control: PC-12, JAR cells. Kidney.

    Known Application: ELISA (For coating, order Ab without BSA)Western Blot (0.5-1 μg/mL)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    NADPH Oxidase 4 (NOX4)
    Andere Bezeichnung
    NOX4 (NOX4 Produkte)
    Synonyme
    KOX antikoerper, KOX-1 antikoerper, RENOX antikoerper, AI648021 antikoerper, nox4 antikoerper, NOX4 antikoerper, NADPH oxidase 4 antikoerper, NOX4 antikoerper, Nox4 antikoerper, nox4 antikoerper, PTRG_09562 antikoerper
    Hintergrund
    The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.
    Molekulargewicht
    70kDa
    Gen-ID
    50507
    UniProt
    Q9NPH5
    Pathways
    Carbohydrate Homeostasis, Smooth Muscle Cell Migration
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