LHCGR Antikörper (N-Term)

Produktnummer ABIN6165116

Produktdetails anti-LHCGR Antikörper

Target: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LHCGR Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC)

Verwendungszweck: Mouse Monoclonal anti-Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR/1417), Purified, with BSA

Produktmerkmale: This antibody recognizes a protein of 78-85 kDa, which is identified as luteinizing hormone/choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Aufreinigung: Purified

Immunogen: Recombinant N-terminal fragment of human LHCGR (exact sequence is proprietary)

Klon: LHCGR-1417

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Immunohistology (formalin) 0.5-1 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
• Flow Cytometry 0.5-1 μg/million cells/0.1 mL
• Immunofluorescence 1-2 μg/mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

HepG2 or Jurkat cells. Ovarian Carcinoma

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 200 μg/mL

Buffer: PBS/0.05 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu LHCGR

Target: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Andere Bezeichnung: Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR Produkte)

Synonyme: HHG antikoerper, LCGR antikoerper, LGR2 antikoerper, LH/CG-R antikoerper, LH/CGR antikoerper, LHR antikoerper, LHRHR antikoerper, LSH-R antikoerper, ULG5 antikoerper, Gpcr19-rs1 antikoerper, LH-R antikoerper, Lhr antikoerper, LSHR antikoerper, lhr antikoerper, GTHR-II antikoerper, zfGTHR-II antikoerper, LHCGR antikoerper, LOC100222883 antikoerper, lh-r antikoerper, LOC100305044 antikoerper, luteinizing hormone/choriogonadotropin receptor antikoerper, luteinizing hormone/choriogonadotropin receptor L homeolog antikoerper, luteinizing hormone receptor antikoerper, LHCGR antikoerper, Lhcgr antikoerper, lhcgr antikoerper, lhcgr.L antikoerper, lhr antikoerper, LOC100305044 antikoerper

Molekulargewicht: 78-85 kDa

Gen-ID: 3973, 468490

UniProt: P22888

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling