S100A9 Antikörper
-
- Target Alle S100A9 Antikörper anzeigen
- S100A9 (S100 Calcium Binding Protein A9 (S100A9))
-
Reaktivität
- Human, Ratte
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser S100A9 Antikörper ist unkonjugiert
-
Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Verwendungszweck
- Mouse Monoclonal anti-S100A9 (47-8D3), Purified, with BSA
- Produktmerkmale
- This MAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffer's cells of the liver and Langerhan's cells of the skin. It also stains the mantle zone B-lymphocytes of the lymph node and spleen, spermatogonia, and chief cells of the stomach. S100A9 is expressed by macrophages in acutely inflamed tissues and in chronic inflammation. It is detected in peripheral blood leukocytes, in neutrophils and granulocytes. It is present at sites of vascular inflammation. S100A9 is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a Calcium-binding protein. It has antimicrobial activity towards bacteria and fungi. It is important for resistance to invasion by pathogenic bacteria. It up-regulates transcription of genes that are under the control of NF-kappa-B. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. It plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Aufreinigung
- Purified
- Immunogen
- Human peripheral blood monocyte components
- Klon
- 47-8D3
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product S100A9 Primärantikörper
-
-
- Applikationshinweise
-
Immunohistology formalin-fixed 0.5-1 μg/mL
- For staining of formalin-fixed, paraffin-embedded tissues, digest with trypsin at 1 mg/mL PBS, 15 min at RT
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Kommentare
-
Liver or histiocytoma
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 200 μg/mL
- Buffer
- PBS/0.05 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
- Target
- S100A9 (S100 Calcium Binding Protein A9 (S100A9))
- Andere Bezeichnung
- S100A9 (S100A9 Produkte)
- Synonyme
- 60B8AG antikoerper, CAGB antikoerper, CFAG antikoerper, CGLB antikoerper, L1AG antikoerper, LIAG antikoerper, MAC387 antikoerper, MIF antikoerper, MRP14 antikoerper, NIF antikoerper, P14 antikoerper, Mrp14 antikoerper, S100A9 antikoerper, MRP-14 antikoerper, p14 antikoerper, 60B8Ag antikoerper, AW546964 antikoerper, BEE22 antikoerper, Cagb antikoerper, GAGB antikoerper, L1Ag antikoerper, S100 calcium binding protein A9 antikoerper, S100 calcium binding protein A9 (calgranulin B) antikoerper, S100A9 antikoerper, S100a9 antikoerper
- Molekulargewicht
- 14 kDa
- Gen-ID
- 6280, 112405
- UniProt
- P06702
- Pathways
- Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteine
-