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S100A9 Antikörper

S100A9 Reaktivität: Human, Ratte IHC, IF, FACS, StM Wirt: Maus Monoclonal S100A9-1075 unconjugated
Produktnummer ABIN6940553
  • Target Alle S100A9 Antikörper anzeigen
    S100A9 (S100 Calcium Binding Protein A9 (S100A9))
    Reaktivität
    • 110
    • 21
    • 19
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 80
    • 45
    • 1
    • 1
    • 1
    • 1
    Maus
    Klonalität
    • 73
    • 56
    Monoklonal
    Konjugat
    • 51
    • 20
    • 12
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser S100A9 Antikörper ist unkonjugiert
    Applikation
    • 59
    • 38
    • 33
    • 27
    • 25
    • 21
    • 13
    • 13
    • 12
    • 9
    • 9
    • 9
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant human S100A9 protein
    Klon
    S100A9-1075
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product S100A9 Primärantikörper
  • Applikationshinweise

    Positive Control: Liver or histiocytoma.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT) (For staining of formalin-fixed, paraffin-embedded tissues, digest with trypsin at 1 mg/mL PBS, 15 min at RT Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    S100A9 (S100 Calcium Binding Protein A9 (S100A9))
    Andere Bezeichnung
    S100A9 (S100A9 Produkte)
    Synonyme
    60B8AG antikoerper, CAGB antikoerper, CFAG antikoerper, CGLB antikoerper, L1AG antikoerper, LIAG antikoerper, MAC387 antikoerper, MIF antikoerper, MRP14 antikoerper, NIF antikoerper, P14 antikoerper, Mrp14 antikoerper, S100A9 antikoerper, MRP-14 antikoerper, p14 antikoerper, 60B8Ag antikoerper, AW546964 antikoerper, BEE22 antikoerper, Cagb antikoerper, GAGB antikoerper, L1Ag antikoerper, S100 calcium binding protein A9 antikoerper, S100 calcium binding protein A9 (calgranulin B) antikoerper, S100A9 antikoerper, S100a9 antikoerper
    Hintergrund
    This MAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupffers cells of the liver and Langerhans cells of the skin. It also stains the mantle zone B-lymphocytes of the lymph node and spleen, spermatogonia, and chief cells of the stomach. S100A9 is expressed by macrophages in acutely inflamed tissues and in chronic inflammation. It is detected in peripheral blood leukocytes, in neutrophils and granulocytes. It is present at sites of vascular inflammation. S100A9 is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a Calcium-binding protein. It has antimicrobial activity towards bacteria and fungi. It is important for resistance to invasion by pathogenic bacteria. It up-regulates transcription of genes that are under the control of NF-kappa-B. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. It plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.
    Molekulargewicht
    14kDa
    Gen-ID
    6280
    UniProt
    P06702
    Pathways
    Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteine
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