CEACAM5 Antikörper
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- Target Alle CEACAM5 Antikörper anzeigen
- CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CEACAM5 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Western Blotting (WB)
- Verwendungszweck
- Mouse Monoclonal anti-CD66 / CEA (COL-1), Purified, BSA-free
- Produktmerkmale
- This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA ) from pleural mesotheliomas (rarely or weakly CEA ). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Aufreinigung
- Purified
- Immunogen
- Human colon carcinoma extract
- Klon
- COL-1
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product CEACAM5 Primärantikörper
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- Applikationshinweise
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Immunohistology formalin-fixed 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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MCF7 or 293T cells. Colon carcinoma
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS (no BSA, no azide)
- Konservierungsmittel
- Azide free
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- Target
- CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))
- Andere Bezeichnung
- CD66 (CEA) (CEACAM5 Produkte)
- Synonyme
- CD66e antikoerper, CEA antikoerper, CEACAM5 antikoerper, CEACAM antikoerper, 1600029H12Rik antikoerper, Psg30 antikoerper, carcinoembryonic antigen related cell adhesion molecule 5 antikoerper, carcinoembryonic antigen antikoerper, carcinoembryonic antigen-related cell adhesion molecule 5 antikoerper, carcinoembryonic antigen-related cell adhesion molecule 8 antikoerper, carcinoembryonic antigen gene family antikoerper, CEACAM5 antikoerper, Ceacam5 antikoerper, LOC100409241 antikoerper, Cea antikoerper
- Hintergrund
- Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, CEACAM5, CD66, Biliary Glycoprotein (BGP-1)
- Molekulargewicht
- 80-200 kDa
- Gen-ID
- 1048, 634, 709196
- UniProt
- P06731
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