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GRIA4 Antikörper (Internal Region)
GRIA4
Reaktivität: Human, Maus, Ratte, Rind (Kuh)
WB, IHC (p), EIA
Wirt: Ziege
Polyclonal
unconjugated
Produktdetails anti-GRIA4 Antikörper
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Target
Alle GRIA4 Antikörper anzeigen
GRIA4
(Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))
Bindungsspezifität
Alle Epitope für GRIA4 Antikörper
Internal Region
Reaktivität
Alle Reaktivitäten für GRIA4 Antikörper
Human, Maus, Ratte, Rind (Kuh)
Wirt
Alle Wirte für GRIA4 Antikörper
Ziege
Klonalität
Alle Klonalitäten für GRIA4 Antikörper
Polyklonal
Konjugat
Alle Konjugate für GRIA4 Antikörper
Dieser GRIA4 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für GRIA4 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Sequenz
C-KKLDQREYPG SETP
Spezifität
This antibody detects Glutamate receptor 4 / GLUR4 (Internal).
Kreuzreaktivität (Details)
Species reactivity (expected):Mouse, Rat and Bovine. Species reactivity (tested):Human.
Aufreinigung
Immunoaffinity chromatography
Immunogen
Peptide with from the internal region of the protein sequence according to NP_000820.3, NP_001070711.1, NP_001070712.1 Genename: GRIA4
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Tris saline, pH 7.3 containing 0.02 % sodium azide as preservative and 0.5 % BSA as stabilizer
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu GRIA4
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Target
GRIA4
(Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))
Andere Bezeichnung
Glutamate Receptor 4 / GLUR4 (GRIA4 Produkte )
Synonyme
GLUR4 antikoerper, GLUR4C antikoerper, GLURD antikoerper, GluA4 antikoerper, GluR4 antikoerper, GluR4d antikoerper, GLUR4/D antikoerper, glur4 antikoerper, GluR-D antikoerper, Glur-4 antikoerper, Glur4 antikoerper, Gluralpha4 antikoerper, spkw1 antikoerper, DKFZp459P0616 antikoerper, glur4a antikoerper, gria4 antikoerper, iGluR4 antikoerper, ZfGluR4b antikoerper, fj46g06 antikoerper, glur4b antikoerper, wu:fj46g06 antikoerper, glutamate ionotropic receptor AMPA type subunit 4 antikoerper, glutamate receptor, ionotropic, AMPA 4 antikoerper, glutamate receptor, ionotropic, AMPA4 (alpha 4) antikoerper, glutamate receptor, ionotropic, AMPA 4a antikoerper, glutamate receptor, ionotropic, AMPA 4b antikoerper, GRIA4 antikoerper, gria4 antikoerper, Gria4 antikoerper, gria4a antikoerper, gria4b antikoerper
Hintergrund
Human glutamate receptor 4 (GRIA4) is a new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. Binding studies showed that human GRIA4 transfected into simian kidney cells (COS-1) exhibits high specific binding for[3H](RS)-alpha-amino- 3-hydroxy-5-methylisoxazole-4-propionic acid ([3H]AMPA) but not [3H]kainate. Ion substitution experiments indicate that hGluR4 receptor-linked ion channels in their homomeric state are permeable to both CA2+ and Na+ ions. Immunoprecipitation studies suggest that GRIA1 exists in situ in the form of a pentamer.Synonyms: AMPA-selective glutamate receptor 4, GRIA4, GluA4, GluR-4, GluR-D, Glutamate receptor ionotropic AMPA4
Gen-ID
2893
NCBI Accession
NP_000820
UniProt
P48058
Pathways
PI3K-Akt Signalweg
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