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KCNJ11 Antikörper (Internal Region)
KCNJ11
Reaktivität: Human, Maus, Ratte, Hund
WB, IHC (p), EIA
Wirt: Ziege
Polyclonal
unconjugated
Produktdetails anti-KCNJ11 Antikörper
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Target
Alle KCNJ11 Antikörper anzeigen
KCNJ11
(Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
Bindungsspezifität
Alle Epitope für KCNJ11 Antikörper
Internal Region
Reaktivität
Alle Reaktivitäten für KCNJ11 Antikörper
Human, Maus, Ratte, Hund
Wirt
Alle Wirte für KCNJ11 Antikörper
Ziege
Klonalität
Alle Klonalitäten für KCNJ11 Antikörper
Polyklonal
Konjugat
Alle Konjugate für KCNJ11 Antikörper
Dieser KCNJ11 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für KCNJ11 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Sequenz
ERRARFVSKK GNC
Kreuzreaktivität (Details)
Species reactivity (expected):Dog, Mouse, RatSpecies reactivity (tested):Human
Aufreinigung
Immunoaffinity chromatography
Immunogen
Synthetic peptide from an internal region of human Kcnj11 Genename: KCNJ11
Top Product
Discover our top product KCNJ11 Primärantikörper
Alternativen
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anti-Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11) (Center) antibody
KCNJ11
Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Schwein
WB, IHC, IF, IC
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Tris saline buffer, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Details zu KCNJ11
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Target
KCNJ11
(Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
Andere Bezeichnung
KCNJ11 (KCNJ11 Produkte )
Synonyme
kir6.2 antikoerper, Kir6.2 antikoerper, mBIR antikoerper, BIR antikoerper, HHF2 antikoerper, IKATP antikoerper, KIR6.2 antikoerper, PHHI antikoerper, TNDM3 antikoerper, potassium voltage-gated channel subfamily J member 11 antikoerper, potassium inwardly-rectifying channel, subfamily J, member 11 antikoerper, potassium inwardly rectifying channel, subfamily J, member 11 antikoerper, KCNJ11 antikoerper, kcnj11 antikoerper, Kcnj11 antikoerper
Hintergrund
Kir6.2/Kcnj11, an ATP sensitive inwardly-rectifying potassium channel, was originally isolated from an insulinoma library. Actual conductance requires association with the sulfonylurea receptor. This receptor is inhibited by sulfonylureas and activated by diazoxide. Mutations in the KNCJ11 gene are found in patients with permanent diabetes mellitus of infancy and hyperinsulinemic hypoglycemia. It is thought that this channel couples metabolism to membrane electrical events fibringing about insulin secretion.Synonyms: ATP-sensitive inward rectifier potassium channel 11, IKATP, Inward rectifier K+ channel Kir6.2, KCNJ11, Potassium channel, inwardly rectifying subfamily J member 11
Gen-ID
9606
UniProt
Q14654
Pathways
Negative Regulation of Hormone Secretion
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