TNFRSF11A Antikörper (AA 466-616)

Produktnummer ABIN6149309

Produktdetails anti-TNFRSF11A Antikörper

Target: TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))

Bindungsspezifität: AA 466-616

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFRSF11A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: RGPLPQCAYG MGLPPEEEAS RTEARDQPED GADGRLPSSA RAGAGSGSSP GGQSPASGNV TGNSNSTFIS SGQVMNFKGD IIVVYVSQTS QEGAAAAAEP MGRPVQEETL ARRDSFAGNG PRFPDPCGGP EGLREPEKAS RPVQEQGGAK A

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 466-616 of human TNFRSF11A (NP_003830.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:2000,IHC,1:100 - 1:100,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TNFRSF11A

Target: TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))

Andere Bezeichnung: TNFRSF11A (TNFRSF11A Produkte)

Synonyme: RANK antikoerper, RGD1563614 antikoerper, TNFRSF11A antikoerper, Ly109 antikoerper, ODFR antikoerper, OFE antikoerper, Rank antikoerper, TRANCE-R antikoerper, mRANK antikoerper, CD265 antikoerper, FEO antikoerper, LOH18CR1 antikoerper, OPTB7 antikoerper, OSTS antikoerper, PDB2 antikoerper, TRANCER antikoerper, TNF receptor superfamily member 11A antikoerper, TNF receptor superfamily member 11a antikoerper, tumor necrosis factor receptor superfamily, member 11a, NFKB activator antikoerper, Tnfrsf11a antikoerper, TNFRSF11A antikoerper

Hintergrund: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus.,TNFRSF11A,CD265,FEO,LOH18CR1,ODFR,OFE,OPTB7,OSTS,PDB2,RANK,TRANCER,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,Growth factor,TNF,Immunology & Inflammation,CD markers,Cytokines,TNF,NF-kB Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,TNFRSF11A

Molekulargewicht: 28 kDa/32 kDa/36 kDa/56 kDa/64 kDa/66 kDa

Gen-ID: 8792

UniProt: Q9Y6Q6

Pathways: NF-kappaB Signalweg