Spindlin 1 Antikörper (AA 1-262)

Produktnummer ABIN6221556

Produktdetails anti-Spindlin 1 Antikörper

Target: Spindlin 1 (SPIN1)

Bindungsspezifität: AA 1-262

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Spindlin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MKTPFGKTPG QRSRADAGHA GVSANMMKKR TSHKKHRSSV GPSKPVSQPR RNIVGCRIQH GWKEGNGPVT QWKGTVLDQV PVNPSLYLIK YDGFDCVYGL ELNKDERVSA LEVLPDRVAT SRISDAHLAD TMIGKAVEHM FETEDGSKDE WRGMVLARAP VMNTWFYITY EKDPVLYMYQ LLDDYKEGDL RIMPDSNDSP PAEREPGEVV DSLVGKQVEY AKEDGSKRTG MVIHQVEAKP SVYFIKFDDD FHIYVYDLVK TS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-262 of human SPIN1 (NP_006708.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Spindlin 1

Target: Spindlin 1 (SPIN1)

Andere Bezeichnung: SPIN1 (SPIN1 Produkte)

Synonyme: SPIN antikoerper, AA553322 antikoerper, AA673430 antikoerper, Spin antikoerper, spin antikoerper, spindlin antikoerper, MGC115436 antikoerper, Spindlin-1 antikoerper, DKFZp459K085 antikoerper, spindlin 1 antikoerper, spindlin 1 L homeolog antikoerper, SPIN1 antikoerper, Spin1 antikoerper, spin1 antikoerper, spin1.L antikoerper

Hintergrund: Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a and acts as an activator of Wnt signaling pathway downstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway. Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes. May play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption.,SPIN1,SPIN,TDRD24,Epigenetics & Nuclear Signaling,Cancer,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,SPIN1

Molekulargewicht: 29 kDa

Gen-ID: 10927

UniProt: Q9Y657