Spindlin 1 Antikörper (AA 1-262)
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- Target Alle Spindlin 1 (SPIN1) Antikörper anzeigen
- Spindlin 1 (SPIN1)
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Bindungsspezifität
- AA 1-262
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Spindlin 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Kreuzreaktivität
- Human
- Aufreinigung
- Antigen Affinity Purified
- Immunogen
- Recombinant Human Spindlin-1 protein (1-262AA)
- Isotyp
- IgG
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anti-Spindlin 1 (SPIN1) (Internal Region) antibody
SPIN1 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (AA 1-262) antibodySPIN1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (Internal Region) antibodySPIN1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (N-Term) antibodySPIN1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (AA 3-100) antibodySPIN1 Reaktivität: Human ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (AA 111-160) antibodySPIN1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (AA 179-228) antibodySPIN1 Reaktivität: Human, Maus, Ratte, Schwein, Kaninchen, Rind (Kuh), Hund, Huhn, Affe, Meerschweinchen, Zebrafisch (Danio rerio), Xenopus laevis, Fledermaus WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (Middle Region) antibodySPIN1 Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Zebrafisch (Danio rerio), Pferd WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Spindlin 1 (SPIN1)
- Andere Bezeichnung
- SPIN1 (SPIN1 Produkte)
- Synonyme
- SPIN antikoerper, AA553322 antikoerper, AA673430 antikoerper, Spin antikoerper, spin antikoerper, spindlin antikoerper, MGC115436 antikoerper, Spindlin-1 antikoerper, DKFZp459K085 antikoerper, spindlin 1 antikoerper, spindlin 1 L homeolog antikoerper, SPIN1 antikoerper, Spin1 antikoerper, spin1 antikoerper, spin1.L antikoerper
- Hintergrund
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Background: Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at \\\'Lys-4\\\' and asymmetrically dimethylated at \\\'Arg-8\\\' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway dowstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (PubMed:24589551). Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006). May play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption.
Aliases: OCR antibody, Ovarian cancer-related protein antibody, SPIN antibody, Spin1 antibody, SPIN1_HUMAN antibody, Spindlin-1 antibody
- UniProt
- Q9Y657
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