SETDB1 Antikörper (AA 1-397)

Produktnummer ABIN6221750

Produktdetails anti-SETDB1 Antikörper

Target: SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

Bindungsspezifität: AA 1-397

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SETDB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Sequenz: MSSLPGCIGL DAATATVESE EIAELQQAVV EELGISMEEL RHFIDEELEK MDCVQQRKKQ LAELETWVIQ KESEVAHVDQ LFDDASRAVT NCESLVKDFY SKLGLQYRDS SSEDESSRPT EIIEIPDEDD DVLSIDSGDA GSRTPKDQKL REAMAALRKS AQDVQKFMDA VNKKSSSQDL HKGTLSQMSG ELSKDGDLIV SMRILGKKRT KTWHKGTLIA IQTVGPGKKY KVKFDNKGKS LLSGNHIAYD YHPPADKLYV GSRVVAKYKD GNQVWLYAGI VAETPNVKNK LRFLIFFDDG YASYVTQSEL YPICRPLKKT WEDIEDISCR DFIEEYVTAY PNRPMVLLKS GQLIKTEWEG TWWKSRVEEV DGSLVRILFL VLFFSTILEA EVGGGGT

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-397 of human SETDB1 (NP_001230420.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:100,IP,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SETDB1

Target: SETDB1 (SET Domain, Bifurcated 1 (SETDB1))

Andere Bezeichnung: SETDB1 (SETDB1 Produkte)

Synonyme: ESET antikoerper, H3-K9-HMTase4 antikoerper, KG1T antikoerper, KMT1E antikoerper, TDRD21 antikoerper, AU022152 antikoerper, mKIAA0067 antikoerper, SETDB1 antikoerper, NV10069 antikoerper, fc07d03 antikoerper, si:ch211-81a5.6 antikoerper, wu:fc07d03 antikoerper, im:7143091 antikoerper, wu:fa04a12 antikoerper, wu:fj80h02 antikoerper, zgc:152899 antikoerper, SET domain bifurcated 1 antikoerper, SET domain, bifurcated 1 antikoerper, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 antikoerper, histone-lysine N-methyltransferase SETDB1 antikoerper, SET domain, bifurcated 1a antikoerper, SET domain bifurcated 1 L homeolog antikoerper, SET domain, bifurcated 1b antikoerper, SETDB1 antikoerper, Setdb1 antikoerper, MLLT11 antikoerper, LOC100120014 antikoerper, LOC100461671 antikoerper, setdb1a antikoerper, setdb1.L antikoerper, setdb1b antikoerper

Hintergrund: This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.,SETDB1,ESET,H3-K9-HMTase4,KG1T,KMT1E,TDRD21,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,SETDB1

Molekulargewicht: 44 kDa/143 kDa

Gen-ID: 9869

UniProt: Q15047