RUNX1T1 Antikörper (AA 100-390)

Produktnummer ABIN6147312

Produktdetails anti-RUNX1T1 Antikörper

Target: RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))

Bindungsspezifität: AA 100-390

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RUNX1T1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GNDISPEIGE RVRTLVLGLV NSTLTIEEFH SKLQEATNFP LRPFVIPFLK ANLPLLQREL LHCARLAKQN PAQYLAQHEQ LLLDASTTSP VDSSELLLDV NENGKRRTPD RTKENGFDRE PLHSEHPSKR PCTISPGQRY SPNNGLSYQP NGLPHPTPPP PQHYRLDDMA IAHHYRDSYR HPSHRDLRDR NRPMGLHGTR QEEMIDHRLT DREWAEEWKH LDHLLNCIMD MVEKTRRSLT VLRRCQEADR EELNYWIRRY SDAEDLKKGG GSSSSHSRQQ SPVNPDPVAL D

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-390 of human RUNX1T1 (NP_783554.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RUNX1T1

Target: RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))

Andere Bezeichnung: RUNX1T1 (RUNX1T1 Produkte)

Synonyme: MTG8 antikoerper, si:ch211-232j17.1 antikoerper, wu:fi14b07 antikoerper, zgc:154044 antikoerper, AML1T1 antikoerper, CBFA2T1 antikoerper, CDR antikoerper, ETO antikoerper, ZMYND2 antikoerper, Cbfa2t1h antikoerper, Cbfa2t1 antikoerper, runt-related transcription factor 1; translocated to, 1 (cyclin D-related) antikoerper, RUNX1 translocation partner 1 L homeolog antikoerper, RUNX1 translocation partner 1 antikoerper, runx1t1 antikoerper, runx1t1.L antikoerper, RUNX1T1 antikoerper, Runx1t1 antikoerper

Hintergrund: This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants.,RUNX1T1,AML1-MTG8,AML1T1,CBFA2T1,CDR,ETO,MTG8,ZMYND2,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,RUNX1T1

Molekulargewicht: 44 kDa/48 kDa/63 kDa/64 kDa/67 kDa/68 kDa

Gen-ID: 862

UniProt: Q06455