RUNX1T1 Produkte
(Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
Kategorien
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8\;21)(q22\;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010].
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Ausgewählte RUNX1T1 Kategorien
RUNX1T1 Antikörper
High quality antibodies with extensive validation data.
RUNX1T1 ELISA Kits
Reliable ELISA kits for a wide range of species.
RUNX1T1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene RUNX1T1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (3)
Kat. Nr.
ABIN560190
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, ChIP, ChIP-seq
Validierungen
- (3)
Kat. Nr.
ABIN5775090
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7165188
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene RUNX1T1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969697
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1150734
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene RUNX1T1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1318994
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1318996
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3093943
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RUNX1T1 Produkten
: "Sperm chromatin proteomics identifies evolutionarily conserved fertility factors." in: Nature, Vol. 443, Issue 7107, pp. 101-5, (2006) (PubMed).: "RNA helicases: regulators of differentiation." in: Clinical biochemistry, Vol. 38, Issue 6, pp. 499-503, (2005) (PubMed).
: "Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity. ..." in: Nature biotechnology, Vol. 23, Issue 3, pp. 344-8, (2005) (PubMed).
: "The oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cells." in: BMC cancer, Vol. 4, pp. 44, (2004) (PubMed).
: "VASA is a specific marker for both normal and malignant human germ cells." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 82, Issue 2, pp. 159-66, (2002) (PubMed).
Synonyme und alternative Namen zu RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (runx1t1), RUNX1 translocation partner 1 L homeolog (runx1t1.L), RUNX1 translocation partner 1 (RUNX1T1), runt-related transcription factor 1; translocated to, 1 (cyclin D-related) (Runx1t1), RUNX1 translocation partner 1 (Runx1t1), AML1T1, CBFA2T1, Cbfa2t1, Cbfa2t1h, CDR, ETO, MTG8, si:ch211-232j17.1, wu:fi14b07, zgc:154044, ZMYND2Bezeichner auf Proteinebene für RUNX1T1
- protein CBFA2T1
- MTG8
- MTG8/ETOb
- expressed during postmitotic spinal neurons, most likely in motorneurons
- acute myelogenous leukemia 1 translocation 1, cyclin-D related
- core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related
- eight twenty one protein
- myeloid translocation gene on 8q22
- zinc finger MYND domain-containing protein 2
- CBFA2T1 identified gene homolog
- acute myelogenous leukemia 1 translocation 1 protein
- core-binding factor, runt domain, alpha subunit 2
- cyclin D-related
- translocated to, 1
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