RUNX1T1 Antikörper (Internal Region, N-Term)

Produktnummer ABIN6655575

Produktdetails anti-RUNX1T1 Antikörper

Target: RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))

Bindungsspezifität: Internal Region, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RUNX1T1 Antikörper ist unkonjugiert

Applikation: ELISA, Chromatin Immunoprecipitation (ChIP)

Aufreinigung: Anti-ETO Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human ETO.  Cross reactivity with ETO from other sources is not known.

Immunogen:

Immunogen: Anti-ETO Antibody was produced in rabbits by repeated immunizations with human ETO using two synthetic peptides containing sequences from the N-terminal and internal region of the protein respectively.

Immunogen Type: Peptide

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-ETO Antibody is suitable for Chromatin Immunoprecipitation and ELISA. Specific conditions for reactivity should be optimized by the end user.

ChIP Dilution: 4 μL/ChIP

ELISA Dilution: 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

0.01 % (w/v) Sodium Azide

Stabilizer: None

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Details zu RUNX1T1

Target: RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))

Andere Bezeichnung: ETO (RUNX1T1 Produkte)

Synonyme: MTG8 antikoerper, si:ch211-232j17.1 antikoerper, wu:fi14b07 antikoerper, zgc:154044 antikoerper, AML1T1 antikoerper, CBFA2T1 antikoerper, CDR antikoerper, ETO antikoerper, ZMYND2 antikoerper, Cbfa2t1h antikoerper, Cbfa2t1 antikoerper, runt-related transcription factor 1; translocated to, 1 (cyclin D-related) antikoerper, RUNX1 translocation partner 1 L homeolog antikoerper, RUNX1 translocation partner 1 antikoerper, runx1t1 antikoerper, runx1t1.L antikoerper, RUNX1T1 antikoerper, Runx1t1 antikoerper

Hintergrund:

Synonyms: Protein CBFA2T1, Cyclin-D-related protein, Eight twenty one protein, Protein ETO, Protein MTG8, Zinc finger MYND domain-containing protein 2, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMTND2

Background: ETO is a transcriptional regulator which belongs to the myeloid translocation gene family. ETO exerts its function by interaction with transcription factors bound to promoters and binding to histone deacetylases. It recruits a range of corepressors to facilitate transcriptional repression. The t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukaemia. This translocation produces a chimeric gene made up of the 5'-region of AML1 and the 3'-region of the ETO gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Anti-ETO Antibody is ideal for research in Gene Expression, Transcription and Cancer.

Gene Name: RUNX1T1

Gen-ID: 862

NCBI Accession: NP_001185554

UniProt: Q06455