RUNX2 Produkte
(Runt-Related Transcription Factor 2 (RUNX2))
Kategorien
This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing. [provided by RefSeq, Jul 2008].
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Ausgewählte RUNX2 Kategorien
RUNX2 Antikörper
High quality antibodies with extensive validation data.
RUNX2 ELISA Kits
Reliable ELISA kits for a wide range of species.
RUNX2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene RUNX2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IHC (p)
Validierungen
- (2)
- (9)
Kat. Nr.
ABIN560185
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IHC (p)
Validierungen
- (5)
- (7)
Kat. Nr.
ABIN514045
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (5)
- (12)
Kat. Nr.
ABIN3016834
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene RUNX2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6959206
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (5)
- (1)
Kat. Nr.
ABIN6959207
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969977
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene RUNX2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124937
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1318998
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1319000
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RUNX2 Produkten
: "The Toll-like receptor ligand, CpG oligodeoxynucleotides, regulate proliferation and osteogenic differentiation of osteoblast." in: Journal of orthopaedic surgery and research, Vol. 15, Issue 1, pp. 327, (2021) (PubMed).: "Human proximal tubular cells can form calcium phosphate deposits in osteogenic culture: role of cell death and osteoblast-like transdifferentiation." in: Cell death discovery, Vol. 5, pp. 57, (2019) (PubMed).
: "Growth Plate Borderline Chondrocytes Behave as Transient Mesenchymal Precursor Cells." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, (2019) (PubMed).
: "Role of RUNX2 transcription factor in epithelial mesenchymal transition in non-small cell lung cancer lung cancer: Epigenetic control of the RUNX2 P1 promoter." in: Tumour biology, Vol. 41, Issue 5, pp. 1010428319851014, (2019) (PubMed).
: "Silent Mating Type Information Regulation 2 Homolog (SIRT1) Influences Osteogenic Proliferation and Differentiation of MC3T3-E1 Cells via Regulation of miR-132-3p." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 25, pp. 2289-2295, (2019) (PubMed).
: "Rotator Cuff Tenocytes Differentiate into Hypertrophic Chondrocyte-Like Cells to Produce Calcium Deposits in an Alkaline Phosphatase-Dependent Manner." in: Journal of clinical medicine, Vol. 8, Issue 10, (2019) (PubMed).
: "Docosahexaenoic Acid (DHA) Inhibits Bone Morphogenetic Protein-2 (BMP-2) Elevated Osteoblast Potential of Metastatic Breast Cancer (MDA-MB-231) Cells in Mammary Microcalcification." in: Nutrition and cancer, pp. 1-11, (2019) (PubMed).
: "Rapid fabrication of vascularized and innervated cell-laden bone models with biomimetic intrafibrillar collagen mineralization." in: Nature communications, Vol. 10, Issue 1, pp. 3520, (2019) (PubMed).
: "Icaritin induces MC3T3-E1 subclone14 cell differentiation through estrogen receptor-mediated ERK1/2 and p38 signaling activation." in: Biomedicine & pharmacotherapy, Vol. 94, pp. 1-9, (2018) (PubMed).
: "mTORC1 activation downregulates FGFR3 and PTH/PTHrP receptor in articular chondrocytes to initiate osteoarthritis." in: Osteoarthritis and cartilage, Vol. 25, Issue 6, pp. 952-963, (2018) (PubMed).
Synonyme und alternative Namen zu RUNX2
runt related transcription factor 2 (RUNX2), runt-related transcription factor 2a (runx2a), runt related transcription factor 2 (Runx2), runt-related transcription factor 2 (Runx2), runt related transcription factor 2 (runx2), runt-related transcription factor 2 (LOC703331), runt-related transcription factor 2 (LOC100549663), runt related transcription factor 2 L homeolog (runx2.L), runt-related transcription factor 2 (RUNX2), AML3, aml3, Cbf, CBF-alpha-1, Cbfa-1, CBFA1, Cbfa1, cbfa1, CCD, ccd, CCD1, ccd1, CLCD, LS3, OSF-2, OSF2, Osf2, osf2, PEA2aA, pea2aa, Pebp2a1, pebp2a1, pebp2a2, PEBP2aA, pebp2aa, pebp2aa1, Pebpa2a, runx2, RUNX2Bezeichner auf Proteinebene für RUNX2
- PEA2-alpha A
- PEBP2-alpha A
- SL3-3 enhancer factor 1 alpha A subunit
- SL3/AKV core-binding factor alpha A subunit
- acute myeloid leukemia 3 protein
- core-binding factor, runt domain, alpha subunit 1
- oncogene AML-3
- osteoblast-specific transcription factor 2
- polyomavirus enhancer-binding protein 2 alpha A subunit
- runt-related transcription factor 2
- transcription factor Runx2a
- AKV core binding factor
- CBF-alpha-1
- PEBP2 alpha A
- core binding factor alpha 1
- runt domain, alpha subunit 1
- core-binding factor subunit alpha-1
- runt related transcription factor 2
- transcription factor Cbfa1
- runt-related factor 2
- core binding factor alpha 1 subunit
- runt-related transcription factor 2-like
- Runx2 spliced isoform
- runt-related transcription factor 2 type I
- runt-related transcription factor 2 type II
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