PTPRF Antikörper (AA 30-190)

Produktnummer ABIN6146462

Produktdetails anti-PTPRF Antikörper

Target: PTPRF (Protein Tyrosine Phosphatase Receptor Type F (PTPRF))

Bindungsspezifität: AA 30-190

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPRF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DSKPVFIKVP EDQTGLSGGV ASFVCQATGE PKPRITWMKK GKKVSSQRFE VIEFDDGAGS VLRIQPLRVQ RDEAIYECTA TNSLGEINTS AKLSVLEEEQ LPPGFPSIDM GPQLKVVEKA RTATMLCAAG GNPDPEISWF KDFLPVDPAT SNGRIKQLRS G

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-190 of human PTPRF (NP_569707.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PTPRF

Target: PTPRF (Protein Tyrosine Phosphatase Receptor Type F (PTPRF))

Andere Bezeichnung: PTPRF (PTPRF Produkte)

Synonyme: LAR antikoerper, AA591035 antikoerper, LARS antikoerper, RPTP-LAR antikoerper, LARFN5C antikoerper, zf-LAR antikoerper, protein tyrosine phosphatase, receptor type F antikoerper, protein tyrosine phosphatase, receptor type, F antikoerper, protein tyrosine phosphatase, receptor type, f, a antikoerper, PTPRF antikoerper, Ptprf antikoerper, ptprfa antikoerper

Hintergrund: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.,PTPRF,BNAH2,LAR,Cancer,Signal Transduction,Endocrine & Metabolism,Neuroscience,Cell Type Marker,Neuron marker,Synapse marker,PTPRF

Molekulargewicht: 211 kDa/212 kDa

Gen-ID: 5792

UniProt: P10586

Pathways: EGFR Signaling Pathway