LECT1 Antikörper (AA 75-334)

Produktnummer ABIN6143133

Produktdetails anti-LECT1 Antikörper

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Bindungsspezifität: AA 75-334

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LECT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: VHYTMSINGK LQDGSMEIDA GNNLETFKMG SGAEEAIAVN DFQNGITGIR FAGGEKCYIK AQVKARIPEV GAVTKQSISS KLEGKIMPVK YEENSLIWVA VDQPVKDNSF LSSKVLELCG DLPIFWLKPT YPKEIQRERR EVVRKIVPTT TKRPHSGPRS NPGAGRLNNE TRPSVQEDSQ AFNPDNPYHQ QEGESMTFDP RLDHEGICCI ECRRSYTHCQ KICEPLGGYY PWPYNYQGCR SACRVIMPCS WWVARILGMV

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 75-334 of human LECT1 (NP_008946.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu LECT1

Target: LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))

Andere Bezeichnung: LECT1 (LECT1 Produkte)

Hintergrund: This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.,CNMD,BRICD3,CHM-I,CHM1,LECT1,MYETS1,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Cytoskeleton,Extracellular Matrix,Bone,Cardiovascular,Angiogenesis,Angiogenic inhibitory factors,LECT1

Molekulargewicht: 36 kDa/37 kDa

Gen-ID: 11061

UniProt: O75829