LECT1 Produkte
(Leukocyte Cell Derived Chemotaxin 1 (LECT1))
Kategorien
This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Ausgewählte LECT1 Kategorien
LECT1 Antikörper
High quality antibodies with extensive validation data.
LECT1 ELISA Kits
Reliable ELISA kits for a wide range of species.
LECT1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene LECT1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7435004
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN389196
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IP
Validierungen
- (2)
Kat. Nr.
ABIN524453
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene LECT1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6957464
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6957465
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Validierungen
Kat. Nr.
ABIN1140560
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene LECT1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1309288
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7396529
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
Kat. Nr.
ABIN7317255
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren LECT1 Produkten
: "Chondromodulin-I derived from the inner meniscus prevents endothelial cell proliferation." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 31, Issue 4, pp. 538-43, (2013) (PubMed).: "Cell-specific epigenetic regulation of ChM-I gene expression: crosstalk between DNA methylation and histone acetylation." in: Biochemical and biophysical research communications, Vol. 365, Issue 1, pp. 124-30, (2007) (PubMed).
: "Chondromodulin-I maintains cardiac valvular function by preventing angiogenesis." in: Nature medicine, Vol. 12, Issue 10, pp. 1151-9, (2006) (PubMed).
: "Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28789-97, (2004) (PubMed).
: "Chondromodulin‑I suppresses tumorigenesis of human osteosarcoma cells." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8542-8548 (PubMed).
Synonyme und alternative Namen zu LECT1
chondromodulin L homeolog (cnmd.L), leukocyte cell derived chemotaxin 1 (lect1), chondromodulin (CNMD), chondromodulin (cnmd), chondromodulin (Cnmd), bricd3, BRICD3, Bricd3, Chm-1, chm-i, CHM-I, ChM-I, chm1, CHM1, chondromodulin-I, Lect1, MGC53801, MGC82444, MYETS1Bezeichner auf Proteinebene für LECT1
- leukocyte cell derived chemotaxin 1
- chondromodulin-I
- chondromodulin-1-like
- chondromodulin-1
- leukocyte cell-derived chemotaxin 1
- BRICHOS domain containing 3
- chondromodulin I
- multiple myeloma tumor suppressor 1
- SCGP
- small cartilage-derived glycoprotein
- Chondromodulin 1
- chM-I
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