Kallikrein 7 Antikörper (AA 30-253)

Produktnummer ABIN6142961

Produktdetails anti-Kallikrein 7 Antikörper

Target: Kallikrein 7 (KLK7)

Bindungsspezifität: AA 30-253

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IIDGAPCARG SHPWQVALLS GNQLHCGGVL VNERWVLTAA HCKMNEYTVH LGSDTLGDRR AQRIKASKSF RHPGYSTQTH VNDLMLVKLN SQARLSSMVK KVRLPSRCEP PGTTCTVSGW GTTTSPDVTF PSDLMCVDVK LISPQDCTKV YKDLLENSML CAGIPDSKKN ACNGDSGGPL VCRGTLQGLV SWGTFPCGQP NDPGVYTQVC KFTKWINDTM KKHR

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-253 of human KLK7 (NP_644806.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Kallikrein 7

Target: Kallikrein 7 (KLK7)

Andere Bezeichnung: KLK7 (KLK7 Produkte)

Synonyme: Prss6 antikoerper, SCCE antikoerper, PRSS6 antikoerper, hK7 antikoerper, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) antikoerper, kallikrein-related peptidase 7 antikoerper, kallikrein related peptidase 7 antikoerper, Klk7 antikoerper, KLK7 antikoerper

Hintergrund: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.,KLK7,PRSS6,SCCE,hK7,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Ubiquitin,KLK7

Molekulargewicht: 19 kDa/27 kDa

Gen-ID: 5650

UniProt: P49862

Pathways: Komplementsystem